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Sequencing techniques

Single-cell RNA-seq data normalization: A benchmarking study

Qinyu Ge, Yuqi Sheng, Junru Lu, Yuwei Yang, Min Pan

published 18 Dec 2025

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SF3B1^K700E mutation in human embryonic stem cells causes aberrant expression of immune-related genes

Mahtab Dastpak, Claudia A. Mimoso, Moein Farshchian, Christina L. Paraggio, Claudia E. Leonard, Shanye Yin, Binkai Chi, Kelsey W. Nassar, R. Grant Rowe, Jiuchun Zhang, Zhonggang Hou, George Q. Daley, Karen Adelman, Robin Reed

published 17 Dec 2025

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Development of a competition assay to assess the in vitro fitness of dengue virus serotypes using an optimized serotype-specific qRT-PCR

Anne-Fleur Griffon, Loeïza Rault, Clément Tanvet, Etienne Simon-Lorière, Myrielle Dupont-Rouzeyrol, Catherine Inizan

published 15 Dec 2025

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UTX/Top2β axis mediated spinal cord microvascular endothelial cells senescence exacerbates spinal cord injury

Dongliang Liu, Yudong Liu, Tianding Wu, Jianzhong Hu

published 12 Dec 2025

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Therapeutic mechanism of Pithecellobium clypearia Benth. on imiquimod-induced psoriasis revealed by tissue transcriptomics in mice

Xiyuan He, Yueting Mo, Peixin Shi, Yini Xu, Mingmei Zhou, Ting Zhang

published 12 Dec 2025

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Comparing RNA extraction protocols from formalin-fixed paraffin-embedded microcore samples

Maxime Golias, Zuzana Krupova, Pierre Defrenaix, Marie-Françoise Heymann, Dominique Heymann

published 08 Dec 2025

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Targeted fetal NGS panel reveals genetic conditions in sonographically normal fetuses: Insights from a large cohort study

Han-Ying Chen, Yi-Ting Wang, Jessica Kang, Yi-Yun Tai, Ti-Jia Yuan, Shin-Yu Lin, Shi-Ming Lin, Chien-Nan Lee, Tsang-Ming Ko

published 02 Dec 2025

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Infiltration of CXCL9+ macrophages confers a favorable prognosis in breast cancer: Insights from an integrated single-cell RNA and bulk RNA sequencing study

Bin Liang, Zhicai Duan, Siyu Long, Peng Zhou

published 01 Dec 2025

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Neural and endothelial cell-derived extracellular vesicles mediate Zika virus genome dissemination and productive infection in vivo

María-Angélica Calderón-Peláez, Myriam L. Velandia-Romero, J. Manuel Matiz-González, Jaime E. Castellanos

published 26 Nov 2025

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Whole genome sequencing, characterization and analysis of coronene degrading bacterial strain Halomonas elongata

Thasneema Rafic, Mohammed Alarawi, Omer Salem Alkhnbashi, Assad Al-Thukair, Ajibola H. Okeyode, Karthikeyan G, Alexis Nzila

published 19 Nov 2025

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ReadSeeker: A DNABERT based de-novo read-level gene predictor

Ben Wulf, Piotr Wojciech Dabrowski

published 13 Nov 2025

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Genetic diversity and population structure of the natural population of Helicoverpa armigera in Northwest China using Genotyping by Sequencing (GBS) technology

Zhongxiong Ning, Jiali He, Jianhao Dong, Weizheng Li, Ruihao Li, Zhengzhen Gao, Dongmei Wang, Haiqiang Li, Bing Liu, Yujiao Wang, Wei Lu

published 06 Nov 2025

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Ionizing radiation leads to exosome secretion in macrophages through MYC-mediated pathways

Hanui Lee, Gyeong Han Jeong, Geun-Joong Kim, Seung Sik Lee, Byung Yeoup Chung, Hyoung-Woo Bai

published 05 Nov 2025

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