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Sequencing techniques

Classification of virulence factors based on dual-channel neural networks with pre-trained language models

Guanghui Li, Peiyang Song, Jiawei Luo, Cheng Liang

published 05 Jan 2026

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Evaluation of RNA extraction and rRNA depletion protocols for RNA-Seq in eleven edible seaweed species from brown, red, and green algae

Rob J. Dekker, Wim A. Ensink, Marina F. van Olst, Selina M. van Leeuwen, Wim C. de Leeuw, Martijs J. Jonker, Timo M. Breit

published 02 Jan 2026

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Next-Gen intestinal parasite detection: Leveraging metataxonomics for improved diagnosis of intestinal protists and helminths

Katherine Bedoya-Urrego, Nicolas Rozo-Montoya, Ana L. Galván-Díaz, Gisela M. Garcia-Montoya, Juan F. Alzate

published 02 Jan 2026

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A methodology for calculating the rarity of diverse proteins based on functional specificity and thermodynamic stability

Brian J. Miller

published 29 Dec 2025

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Centriflaken: An automated data analysis pipeline for assembly and in silico analyses of foodborne pathogens from metagenomic samples

Kranti Konganti, Julie A. Kase, Narjol Gonzalez-Escalona

published 23 Dec 2025

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Single-cell RNA-seq data normalization: A benchmarking study

Qinyu Ge, Yuqi Sheng, Junru Lu, Yuwei Yang, Min Pan

published 18 Dec 2025

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SF3B1^K700E mutation in human embryonic stem cells causes aberrant expression of immune-related genes

Mahtab Dastpak, Claudia A. Mimoso, Moein Farshchian, Christina L. Paraggio, Claudia E. Leonard, Shanye Yin, Binkai Chi, Kelsey W. Nassar, R. Grant Rowe, Jiuchun Zhang, Zhonggang Hou, George Q. Daley, Karen Adelman, Robin Reed

published 17 Dec 2025

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Development of a competition assay to assess the in vitro fitness of dengue virus serotypes using an optimized serotype-specific qRT-PCR

Anne-Fleur Griffon, Loeïza Rault, Clément Tanvet, Etienne Simon-Lorière, Myrielle Dupont-Rouzeyrol, Catherine Inizan

published 15 Dec 2025

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UTX/Top2β axis mediated spinal cord microvascular endothelial cells senescence exacerbates spinal cord injury

Dongliang Liu, Yudong Liu, Tianding Wu, Jianzhong Hu

published 12 Dec 2025

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Therapeutic mechanism of Pithecellobium clypearia Benth. on imiquimod-induced psoriasis revealed by tissue transcriptomics in mice

Xiyuan He, Yueting Mo, Peixin Shi, Yini Xu, Mingmei Zhou, Ting Zhang

published 12 Dec 2025

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Comparing RNA extraction protocols from formalin-fixed paraffin-embedded microcore samples

Maxime Golias, Zuzana Krupova, Pierre Defrenaix, Marie-Françoise Heymann, Dominique Heymann

published 08 Dec 2025

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Targeted fetal NGS panel reveals genetic conditions in sonographically normal fetuses: Insights from a large cohort study

Han-Ying Chen, Yi-Ting Wang, Jessica Kang, Yi-Yun Tai, Ti-Jia Yuan, Shin-Yu Lin, Shi-Ming Lin, Chien-Nan Lee, Tsang-Ming Ko

published 02 Dec 2025

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Infiltration of CXCL9+ macrophages confers a favorable prognosis in breast cancer: Insights from an integrated single-cell RNA and bulk RNA sequencing study

Bin Liang, Zhicai Duan, Siyu Long, Peng Zhou

published 01 Dec 2025

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