Advertisement

Browse Subject Areas

?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

Ribonucleoproteins

Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines

Spencer C. Wei, Aaron J. Cantor, Jack Walleshauser, Rina Mepani, Kory Melton, Ashil Bans, Prachi Khekare, Suhani Gupta, Jonathan Wang, Craig Soares, Radwan Kiwan, Jieun Lee, Shannon McCawley, Vihasi Jani, Weng In Leong, Pawan K. Shahi, Jean Chan, Pierre Boivin, Peter Otoupal, Bikash R. Pattnaik, David M. Gamm, Krishanu Saha, Benjamin G. Gowen, Mary Haak-Frendscho, Mary J. Janatpour, Adam P. Silverman

published 24 Jun 2025

Loading metrics information...

Metrics unavailable. Please check back later.

A simple validation and screening method for CRISPR/Cas9-mediated gene editing in mouse embryos to facilitate genetically modified mice production

Dawid Winiarczyk, Hossein Khodadadi, Paweł Leszczyński, Hiroaki Taniguchi

published 27 Mar 2025

Loading metrics information...

Metrics unavailable. Please check back later.

Systematic identification and characterization of high efficiency Cas9 guide RNAs for therapeutic targeting of ADAR

Benjamin G. Gowen, Kory Melton, Weng In Leong, Prachi Khekare, Shannon McCawley, Jean Chan, Pierre Boivin, Vihasi Jani, Aaron J. Cantor, Akshay Tambe, Mary Haak-Frendscho, Mary J. Janatpour, Spencer C. Wei

published 24 Feb 2025

Loading metrics information...

Metrics unavailable. Please check back later.

Development of an optimized protocol for generating knockout cancer cell lines using the CRISPR/Cas9 system, with emphasis on transient transfection

Seyed Alireza Mousavi Kahaki, Nayereh Ebrahimzadeh, Hossein Fahimi, Arfa Moshiri

published 14 Nov 2024

Loading metrics information...

Metrics unavailable. Please check back later.

Mechanisms of active diffusion of vesicular stomatitis virus inclusion bodies and cellular early endosomes in the cytoplasm of mammalian cells

Steven J. Moran, Ryan Oglietti, Kathleen C. Smith, Jed C. Macosko, George Holzwarth, Douglas S. Lyles

published 14 Mar 2024

Loading metrics information...

Metrics unavailable. Please check back later.

Gene knock-outs in human CD34+ hematopoietic stem and progenitor cells and in the human immune system of mice

Daniel A. Kuppers, Jonathan Linton, Sergio Ortiz Espinosa, Kelly M. McKenna, Anthony Rongvaux, Patrick J. Paddison

published 28 Jun 2023

Loading metrics information...

Metrics unavailable. Please check back later.

A precise gene delivery approach for human induced pluripotent stem cells using Cas9 RNP complex and recombinant AAV6 donor vectors

Koollawat Chupradit, Nontaphat Thongsin, Chatchai Tayapiwatana, Methichit Wattanapanitch

published 07 Jul 2022

Loading metrics information...

Metrics unavailable. Please check back later.

Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles

Andrew R. Castle, Serene Wohlgemuth, Luis Arce, David Westaway

published 07 Jun 2022

Loading metrics information...

Metrics unavailable. Please check back later.

Genome editing using preassembled CRISPR-Cas9 ribonucleoprotein complexes in Fusarium graminearum

Nahyun Lee, Jiyeun Park, Jung-Eun Kim, Ji Young Shin, Kyunghun Min, Hokyoung Son

published 03 Jun 2022

Loading metrics information...

Metrics unavailable. Please check back later.

Protocol for assessment of the efficiency of CRISPR/Cas RNP delivery to different types of target cells

Marina A. Tyumentseva, Aleksandr I. Tyumentsev, Vasiliy G. Akimkin

published 09 Nov 2021

Loading metrics information...

Metrics unavailable. Please check back later.

Pursuit of chlorovirus genetic transformation and CRISPR/Cas9-mediated gene editing

Eric A. Noel, Donald P. Weeks, James L. Van Etten

published 21 Oct 2021

Loading metrics information...

Metrics unavailable. Please check back later.

Markers of acute toxicity of DDT exposure in pancreatic beta-cells determined by a proteomic approach

Nela Pavlikova, Jan Sramek, Michael Jelinek, Petr Halada, Jan Kovar

published 26 Oct 2020

Loading metrics information...

Metrics unavailable. Please check back later.

Interaction between influenza A virus nucleoprotein and PB2 cap-binding domain is mediated by RNA

Wun-Chung Szeto, Ho-Pan Hsia, Yun-Sang Tang, Pang-Chui Shaw

published 28 Sep 2020

Loading metrics information...

Metrics unavailable. Please check back later.

Advertisement

Create a weekly email alert for: Ribonucleoproteins

You can change these options by clicking profile then "Alerts and Notifications"