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Receptor-ligand binding assay

Characterization of Fibrodysplasia Ossificans Progessiva relevant Acvr1/Acvr2 Activin receptors in medaka (Oryzias latipes)

Michael Trumpp, Wen Hui Tan, Wiktor Burdzinski, Yara Basler, Jerome Jatzlau, Petra Knaus, Christoph Winkler

published 14 Sep 2023

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A microfluidics-based method for isolation and visualization of cells based on receptor-ligand interactions

Long Dao, Qingnan Zhao, Jiemiao Hu, Xueqing Xia, Qing Yang, Shulin Li

published 06 Oct 2022

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A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology

Teresa L. Burgess, Joshua D. Amason, Jeffrey S. Rubin, Damien Y. Duveau, Laurence Lamy, David D. Roberts, Catherine L. Farrell, James Inglese, Craig J. Thomas, Thomas W. Miller

published 02 Apr 2020

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Hidden bias in the DUD-E dataset leads to misleading performance of deep learning in structure-based virtual screening

Lieyang Chen, Anthony Cruz, Steven Ramsey, Callum J. Dickson, Jose S. Duca, Viktor Hornak, David R. Koes, Tom Kurtzman

published 20 Aug 2019

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The collαgen III fibril has a “flexi-rod” structure of flexible sequences interspersed with rigid bioactive domains including two with hemostatic roles

J. Des Parkin, James D. San Antonio, Anton V. Persikov, Hayat Dagher, Raymond Dalgleish, Shane T. Jensen, Xavier Jeunemaitre, Judy Savige

published 13 Jul 2017

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A Natural Mutation in Helix 5 of the Ligand Binding Domain of Glucocorticoid Receptor Enhances Receptor-Ligand Interaction

Henry Reyer, Siriluck Ponsuksili, Ellen Kanitz, Ralf Pöhland, Klaus Wimmers, Eduard Murani

published 13 Oct 2016

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Functional Stability of the Human Kappa Opioid Receptor Reconstituted in Nanodiscs Revealed by a Time-Resolved Scintillation Proximity Assay

Randi Westh Hansen, Xiaole Wang, Agnieszka Golab, Olivier Bornert, Christine Oswald, Renaud Wagner, Karen Laurence Martinez

published 01 Apr 2016

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Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor

Marianne Mathäs, Christian Nußhag , Oliver Burk, Ute Gödtel-Armbrust, Holger Herlyn, Leszek Wojnowski, Björn Windshügel

published 05 May 2014

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The Interaction of CRM1 and the Nuclear Pore Protein Tpr

Charles L. Zhao, Seyed Hanif Mahboobi, Ruhollah Moussavi-Baygi, Mohammad R. K. Mofrad

published 10 Apr 2014

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Kinetic Characterization of an Intestinal Trefoil Factor Receptor

Zhang Yong, Wang Lin, Sun Yong, Liang Guang-ping, Wu Dan, Lv Shang-jun, Wu Wei, Peng Xi

published 23 Sep 2013

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Assessment and Challenges of Ligand Docking into Comparative Models of G-Protein Coupled Receptors

Elizabeth Dong Nguyen, Christoffer Norn, Thomas M. Frimurer, Jens Meiler

published 02 Jul 2013

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Influence of GABA_A Receptor α Subunit Isoforms on the Benzodiazepine Binding Site

Benjamin P. Lüscher, Roland Baur, Maurice Goeldner, Erwin Sigel

published 27 Jul 2012

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Cyproheptadine Enhances the I_K of Mouse Cortical Neurons through Sigma-1 Receptor-Mediated Intracellular Signal Pathway

Yan-Lin He, Chun-Lei Zhang, Xiao-Fei Gao, Jin-Jing Yao, Chang-Long Hu, Yan-Ai Mei

published 23 Jul 2012

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