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Receptor-ligand binding assay

Characterization of Fibrodysplasia Ossificans Progessiva relevant Acvr1/Acvr2 Activin receptors in medaka (Oryzias latipes)

Michael Trumpp, Wen Hui Tan, [ ... ], Christoph Winkler

A microfluidics-based method for isolation and visualization of cells based on receptor-ligand interactions

Long Dao, Qingnan Zhao, [ ... ], Shulin Li

A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology

Teresa L. Burgess, Joshua D. Amason, [ ... ], Thomas W. Miller

Hidden bias in the DUD-E dataset leads to misleading performance of deep learning in structure-based virtual screening

Lieyang Chen, Anthony Cruz, [ ... ], Tom Kurtzman

The collαgen III fibril has a “flexi-rod” structure of flexible sequences interspersed with rigid bioactive domains including two with hemostatic roles

J. Des Parkin, James D. San Antonio, [ ... ], Judy Savige

A Natural Mutation in Helix 5 of the Ligand Binding Domain of Glucocorticoid Receptor Enhances Receptor-Ligand Interaction

Henry Reyer, Siriluck Ponsuksili, [ ... ], Eduard Murani

Functional Stability of the Human Kappa Opioid Receptor Reconstituted in Nanodiscs Revealed by a Time-Resolved Scintillation Proximity Assay

Randi Westh Hansen, Xiaole Wang, [ ... ], Karen Laurence Martinez

Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor

Marianne Mathäs, Christian Nußhag , [ ... ], Björn Windshügel

The Interaction of CRM1 and the Nuclear Pore Protein Tpr

Charles L. Zhao, Seyed Hanif Mahboobi, Ruhollah Moussavi-Baygi, Mohammad R. K. Mofrad

Kinetic Characterization of an Intestinal Trefoil Factor Receptor

Zhang Yong, Wang Lin, [ ... ], Peng Xi

Assessment and Challenges of Ligand Docking into Comparative Models of G-Protein Coupled Receptors

Elizabeth Dong Nguyen, Christoffer Norn, Thomas M. Frimurer, Jens Meiler

Influence of GABA_A Receptor α Subunit Isoforms on the Benzodiazepine Binding Site

Benjamin P. Lüscher, Roland Baur, Maurice Goeldner, Erwin Sigel

Cyproheptadine Enhances the I_K of Mouse Cortical Neurons through Sigma-1 Receptor-Mediated Intracellular Signal Pathway

Yan-Lin He, Chun-Lei Zhang, [ ... ], Yan-Ai Mei

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