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Protein kinases

Grb2 phosphorylation antagonizes EGFR-driven ras activation by interfering with condensate assembly

Henry T. Phan, Chun-Wei Lin, [ ... ], Jay T. Groves

RA-PLA: Retrieval-augmented graph convolutional networks for protein-ligand binding affinity prediction

Karim Abbasi, Hossein Banadkuki, Reza Sepahvand, Shima Rashidi

Mechanistic evaluation of NSC 57774 as a SHP2 inhibitor in gastric cancer: Multi-pathway signaling modulation in vitro

Ghalia Khoder, Rose Ghemrawi, [ ... ], Mostafa Khair

G-protein coupled receptor, signal and signal-transduction related transcript mapping in nigral volume and pigmented neurons reveals a potential deficit of nigral feedback signals associated with Parkinson’s disease

John M. Haynes

HIV-1 Nef inhibits the JAK/STAT signaling pathway by inducing proteasomal degradation of STAT1

Roger L. Rodrigues, Mara E. da Silva-Januário, [ ... ], Luis L. P. daSilva

Higher frequency of subclonal anti-EGFR resistance mutations in post-treatment samples from patients with colorectal cancer liver metastases following anti-EGFR-based conversion chemotherapy

Christoph Steup, Antonia Mondorf, [ ... ], Christine Koch

Inhibition of purine nucleoside and nucleobase transporters by tyrosine kinase inhibitors

Nayiar Shahid, Chan H. Kim, [ ... ], James R. Hammond

Phosphorylation landscape of dengue virus proteins and their implications in protein-protein interactions

Prakhar Agrawal, Rahul Yadav, Arumugam Madhumalar, Ganesan Senthil Kumar

Characterization of the TREM-1 signaling landscape in human neutrophils

Frederic Ries, Matthias Klein, [ ... ], Markus P. Radsak

Genome-wide association study revealed genomic regions associated with tuber quality traits in water yam (Dioscorea alata L.)

Fatoumata Ouattara, Paterne A. Agre, [ ... ], Ranjana Bhattacharjee

Identification of cCMP- and cUMP-binding proteins using cCMP and cUMP coupled to agarose and biotin matrices

Sabine Wolter, Martin Neumann, [ ... ], Roland Seifert

Evaluating the pentapharmacological potency of otamixaban against lung cancer CDK2, transferase, oxidoreductase and signalling proteins

Hanadi M. Baeissa, Tahani Bakhsh, [ ... ], Deeba Shamim Jairajpuri

Integrated analysis of ARHGAP6 potential function and prognostic value in acute myeloid leukemia

Debin Yang, Yuanzhe Li, Ping Ma, Fankai Xiao

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