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Protein domains

Computational prediction of binding affinity and structural impact of three Pakistani SARS-CoV-2 spike RBD variants on human ACE2 interaction

Muhammad Usama, Muhammad Azeem, Ghulam Mustafa

published 01 Apr 2026

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Proteome-based investigation of O-GlcNAcylation in a C. elegans model of ageing and Alzheimer’s disease: Functional support for earlier hypothesis-generating findings

Fernando Garcia Olivera

published 30 Mar 2026

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Bacteriophage T4 gene 32 protein: Insights into its interaction with ssDNA, binding cooperativity, and conformational change

Jules Guei, Michael P. Chapman, Paul N. Brothers, Shital Desai, Richard L. Karpel

published 11 Feb 2026

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Regulation of tension-dependent localization of LATS1 and LATS2 to adherens junctions

Chamika De Silva, Brian A. Kelch, Dannel McCollum

published 02 Feb 2026

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In-silico characterization of deleterious non-synonymous SNPs in the human S1PR1 gene reveals structural instability and altered ligand affinity

Sangram Biswas, Dipankar Sardar, Md. Arju Hossain, Soharth Hasnat, Arif Hossain Ramjan, Ummah Kulsum Nazifa, Fatema-Tuz Zohora, Ishrat Jahan Esha, Chandrika Mondal, Abdul Barik, M. Nazmul Hoque

published 02 Feb 2026

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Isolation and characterization of four novel Vibrio parahaemolyticus bacteriophages from oysters

Joud Aldaroub, Chrissy M. Walsky, Rylee E. Ewell, Frank O. Aylward, Ann M. Stevens, Alison Kernell Burke

published 29 Dec 2025

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Potential FSH-mediated molecular pathway to regulate follicle development in striped hamsters (Cricetulus barabensis) supported by strong correlative evidence

Huiliang Xue, Yunjiao Zheng, Chao Fan, Jinhui Xu, Lei Chen, Ming Wu, Laixiang Xu

published 29 Dec 2025

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Deciphering the pathogenicity of three NKX2-1 variants in ultra-severe forms of childhood interstitial lung disease

Yohan David Soreze, Tifenn Desroziers-Louedec, Aurore Carré, Farah Diab, Aphrodite Daskalopoulou, Julie Starck, Valérie Nau, Marie Legendre, Sonia-Athina Karabina, Véronique Houdouin, Aurore Coulomb-L’herminé, Camille Louvrier, Nadia Nathan

published 19 Dec 2025

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A putative membrane-associated YdjB-like protein from Salmonella enterica exhibits a non-canonical ACT-like fold

Ju Hyeong Kim, Yong Jun Kang, Young Woo Kang, So Eun Park, Hyo Been Jin, Eunmi Hong, Hyun Ho Park

published 11 Dec 2025

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Unveiling the Plasmodium inositol (pyro)phosphate pathway: Highlighting inositol polyphosphate multikinase as a novel therapeutic target for malaria

Abigail Obuobi, Neils B. Quashie, Nancy Odurowah Duah-Quashie, Jon R. Sayers

published 10 Dec 2025

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Housing environment bilaterally alters transcriptomic profile in the rat hippocampal CA1 region

Azusa Kubota, Kentaro Kojima, Shinnosuke Koketsu, Takayuki Kannon, Takehiro Sato, Kazuyoshi Hosomichi, Yoshiaki Shinohara, Atsushi Tajima

published 04 Dec 2025

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Genome-wide identification and functional characterization of NPR1-like genes in Actinidia deliciosa

Weimin Zhong, Yuexia Wang, Shiming Han, Jihong Dong, Yumei Fang, Xiaoling Xu, Muhammad Umar Rasheed, Aiman Malik, Qurban Ali, Muhammad Ashfaq, Jia Zhou

published 13 Nov 2025

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Molecular and evolutionary determinants for protein interaction within a class II aldolase/Adducin domain

Marina E. Seheon, Amalia S. Parra, Christopher A. Johnston

published 10 Nov 2025

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