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Proteasomes

Inhibition of Proteasomal Degradation of Rpn4 Impairs Nonhomologous End-Joining Repair of DNA Double-Strand Breaks

Donghong Ju, Xiaogang Wang, Seung-Wook Ha, Jiejun Fu, Youming Xie

published 01 Apr 2010

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Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1^H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking

Shinji Hadano, Asako Otomo, Ryota Kunita, Kyoko Suzuki-Utsunomiya, Akira Akatsuka, Masato Koike, Masashi Aoki, Yasuo Uchiyama, Yasuto Itoyama, Joh-E Ikeda

published 22 Mar 2010

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In Vivo Accumulation of Helicobacter pylori Products, NOD1, Ubiquitinated Proteins and Proteasome in a Novel Cytoplasmic Structure

Vittorio Necchi, Patrizia Sommi, Vittorio Ricci, Enrico Solcia

published 16 Mar 2010

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Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population

Michele Mishto, Elena Bellavista, Claudia Ligorio, Kathrin Textoris-Taube, Aurelia Santoro, Mara Giordano, Sandra D'Alfonso, Florinda Listì, Benedetta Nacmias, Elena Cellini, Maurizio Leone, Luigi M.E. Grimaldi, Chiara Fenoglio, Federica Esposito, Filippo Martinelli-Boneschi, Daniela Galimberti, Elio Scarpini, Ulrike Seifert, Maria Pia Amato, Calogero Caruso, Maria P. Foschini, Peter M. Kloetzel, Claudio Franceschi

published 18 Feb 2010

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17-AAG Induces Cytoplasmic α-Synuclein Aggregate Clearance by Induction of Autophagy

Michael Riedel, Olaf Goldbaum, Lisa Schwarz, Sebastian Schmitt, Christiane Richter-Landsberg

published 18 Jan 2010

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Prokayrotic Ubiquitin-Like Protein (Pup) Proteome of Mycobacterium tuberculosis

Richard A. Festa, Fiona McAllister, Michael J. Pearce, Julian Mintseris, Kristin E. Burns, Steven P. Gygi, K. Heran Darwin

published 06 Jan 2010

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Discovery of Novel Proteasome Inhibitors Using a High-Content Cell-Based Screening System

Irena Lavelin, Avital Beer, Zvi Kam, Varda Rotter, Moshe Oren, Ami Navon, Benjamin Geiger

published 30 Dec 2009

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N-Terminal Deletion of Peptide:N-Glycanase Results in Enhanced Deglycosylation Activity

Shengjun Wang, Fengxue Xin, Xiaoyue Liu, Yuxiao Wang, Zhenyi An, Qingsheng Qi, Peng George Wang

published 16 Dec 2009

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Immunoproteasome Overexpression Underlies the Pathogenesis of Thyroid Oncocytes and Primary Hypothyroidism: Studies in Humans and Mice

Hiroaki J. Kimura, Cindy Y. Chen, Shey-Cherng Tzou, Roberto Rocchi, Melissa A. Landek-Salgado, Koichi Suzuki, Miho Kimura, Noel R. Rose, Patrizio Caturegli

published 17 Nov 2009

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Usa1 Protein Facilitates Substrate Ubiquitylation through Two Separate Domains

Ikjin Kim, Yue Li, Paulina Muniz, Hai Rao

published 29 Oct 2009

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COMMD1 Promotes pVHL and O₂-Independent Proteolysis of HIF-1α via HSP90/70

Bart van de Sluis, Arjan J. Groot, Jeroen Vermeulen, Elsken van der Wall, Paul J. van Diest, Cisca Wijmenga, Leo W. Klomp, Marc Vooijs

published 05 Oct 2009

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Effects of Endotoxaemia on Protein Metabolism in Rat Fast-Twitch Skeletal Muscle and Myocardium

Andrew J. Murton, Nima Alamdari, Sheila M. Gardiner, Dumitru Constantin-Teodosiu, Robert Layfield, Terence Bennett, Paul L. Greenhaff

published 14 Sep 2009

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FoxM1 Is a General Target for Proteasome Inhibitors

Uppoor G. Bhat, Marianna Halasi, Andrei L. Gartel

published 12 Aug 2009

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