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Pro-drugs

Investigation of hydrolysis of olmesartan medoxomil in different pH buffers by simultaneously measuring olmesartan medoxomil and olmesartan

Lauren Landry, Xiaowei Dong

Pharmacokinetics of isavuconazonium sulfate and its active metabolite isavuconazole in healthy dogs

Erin McQuinn, Jonathan P. Mochel, [ ... ], Jean-Sébastien Palerme

Physicochemical investigation of a novel curcumin diethyl γ-aminobutyrate, a carbamate ester prodrug of curcumin with enhanced anti-neuroinflammatory activity

Ponsiree Jithavech, Piyapan Suwattananuruk, [ ... ], Pornchai Rojsitthisak

Pharmacological and pharmacokinetic profile of the novel ocular hypotensive prodrug CKLP1 in Dutch-belted pigmented rabbits

Uttio Roy Chowdhury, Rachel A. Kudgus, [ ... ], Michael P. Fautsch

Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose

Sarah Piel, Imen Chamkha, [ ... ], Magnus J. Hansson

Luciferase-based reporting of suicide gene activity in murine mesenchymal stem cells

Dario Gerace, Rosetta Martiniello-Wilks, Rosaline Habib, Ann Margaret Simpson

Design of stable magnetic hybrid nanoparticles of Si-entrapped HRP

Sonali Correa, Sara Puertas, [ ... ], Lorena Betancor

Predicting inadequate postoperative pain management in depressed patients: A machine learning approach

Arjun Parthipan, Imon Banerjee, [ ... ], Tina Hernandez-Boussard

A genetically engineered microRNA-34a prodrug demonstrates anti-tumor activity in a canine model of osteosarcoma

Fernando Alegre, Amanda R. Ormonde, [ ... ], Luke A. Wittenburg

Prodrugs for colon-restricted delivery: Design, synthesis, and in vivo evaluation of colony stimulating factor 1 receptor (CSF1R) inhibitors

Dawn M. George, Raymond J. Huntley, [ ... ], Jeremy J. Edmunds

Novel multipurpose pod-intravaginal ring for the prevention of HIV, HSV, and unintended pregnancy: Pharmacokinetic evaluation in a macaque model

James M. Smith, John A. Moss, [ ... ], Marc M. Baum

Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase

Aiping Bai, Cungui Mao, [ ... ], Yusuf A. Hannun

Rapid Recovery of Visual Function Associated with Blue Cone Ablation in Zebrafish

Gordon F. Hagerman, Nicole C. L. Noel, [ ... ], W. Ted Allison

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