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PPAR signaling

Multi-omics analysis identifies PPARα as a key inhibitor of hepatocyte ferroptosis in sepsis-associated liver injury

Shi-Ling He, Jian-Chuan Lin, Gao-Fang Wu, He-fan He

published 19 Feb 2026

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Unveiling the molecular mechanisms of burn injury through integrated single-cell and bulk transcriptomic analysis

Xiaoyu Zhu, Neng Huang, Yanyan Pan, Xin Le, Shengyong Cui, Jiliang Li, Youfen Fan

published 27 Jan 2026

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Plasma-activated media inhibits epithelial-mesenchymal transition and ameliorates intestinal fibrosis through the PPARγ/TGF-β1/SMAD3 pathway

Yi You, Yaping Shen, Yan Yang, Xiaoyang Wei, Yuheng Zhou, Foxing Tan, Longcheng Deng, Haolin Du, Sen Wang, Cheng Wang, Yan Huang

published 22 Oct 2025

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Mechanism of Huanglian Wendan Decoction in ameliorating non-alcoholic fatty liver disease via modulating gut microbiota-mediated metabolic reprogramming and activating the LKB1/AMPK pathway

Jianping Zhu, Yuzhen Chen, Yidi Han, Ji Li

published 02 Sep 2025

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Therapeutic role of Crateva religiosa in diabetic nephropathy: Insights into key signaling pathways

Muhammad Ali, Hafiz M. Irfan, Alamgeer, Aman Ullah, Magda H. Abdellattif, Mahmoud Elodemi, Mohammad Zubair, Ajmal Khan, Ahmed Al-Harrasi

published 28 May 2025

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LIPG-mediated regulation of lipid deposition and proliferation in goat intramuscular preadipocytes involves the PPARα signaling pathway

Yinggui Wang, Lian Huang, JiangJiang Zhu, Wenyang Zhang, Yinmei Tang, Changheng Yang, Yaqiu Lin, Yong Wang, Hua Xiang

published 13 Feb 2025

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Transcriptome comparison revealed the difference in subcutaneous fat metabolism of Qinghai yak under different feeding conditions

Weiqin Ding, Yonggang Sun, Yincang Han, Yaqian Liu, Shengwei Jin

published 05 Dec 2024

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Botanical formulation HX110B ameliorates PPE-induced emphysema in mice via regulation of PPAR/RXR signaling pathway

Soojin Lee, Chang Hyung Lee, Jungkyu Lee, Yoonseon Jeong, Jong-Hyung Park, In-Jeong Nam, Doo Suk Lee, Hyun Myung Lee, Soo-Yeon Ahn, Eujung Kim, Seungyeon Jeong, Seung-Shin Yu, Wonwoo Lee

published 25 Jul 2024

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Molecular regulation of PPARγ/RXRα signaling by the novel cofactor ZFP407

Alyssa Charrier, Jeremiah Ockunzzi, Leighanne Main, Siddharth V. Ghanta, David A. Buchner

published 23 May 2024

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Nonalcoholic steatohepatitis-associated hepatocarcinogenesis in mice fed a modified choline-deficient, methionine-lowered, L-amino acid-defined diet and the role of signal changes

Noriko Suzuki-Kemuriyama, Akari Abe, Sae Nakane, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae

published 03 Aug 2023

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Molecular mechanism of the anti-gastric cancer activity of 1,2,3,6-tetra-O-galloyl-β-D-glucose isolated from Trapa bispinosa Roxb. shell in vitro

Limei Wang, Dongjie Yin, Yanhui Fan, Ting Min, Yang Yi, Hongxun Wang

published 02 Jun 2022

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Network pharmacology of bioactives from Sorghum bicolor with targets related to diabetes mellitus

Ki Kwang Oh, Md. Adnan, Dong Ha Cho

published 31 Dec 2020

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Anti-obesity effects of Spirulina platensis protein hydrolysate by modulating brain-liver axis in high-fat diet fed mice

Bingli Zhao, Yujiao Cui, Xiaodan Fan, Ping Qi, Chunchen Liu, Xuesong Zhou, Xuewu Zhang

published 20 Jun 2019

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