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Post-translational modification

Advanced machine learning-guided optimization platform for high-yield soluble expression of Pseudomonas aeruginosa exotoxin A in engineered Escherichia coli strains

Shah Faisal Mohammad, Fawad Ali, Mamirkulova Shynara

Human resistin is critical to activation of the NLRP3 inflammasome in macrophages

Udeshika Kariyawasam, Winson Lam, [ ... ], Roger A. Johns

Identification of neuronatin as a SERCA2b regulin-like protein and assessment of its aggregation propensity via coarse grained simulations

Omar Ben Mariem, Lara Coppi, [ ... ], Maurizio Crestani

Proteome-based investigation of O-GlcNAcylation in a C. elegans model of ageing and Alzheimer’s disease: Functional support for earlier hypothesis-generating findings

Fernando Garcia Olivera

Plasma heme pool compartmentalization is linked to pathophysiology in Sickle Cell Disease

Moritz Saxenhofer, Daniel Couto, [ ... ], Alexander Schaub

Age-associated accumulation of carbamylation-derived products in tissues is independent from the myeloperoxidase pathway in mice

Christine Pietrement, Anaïs Okwieka, [ ... ], Stéphane Jaisson

Computational modelling of the equine arteritis virus GP5/M Dimer: Implications for immune evasion and virulence

Michael Veit, Anna Karolina Matczuk

Myc and Skp2 overexpression promotes p27 ubiquitination and degradation in Ewing Sarcoma

Yuta Kubota, Masanori Kawano, [ ... ], Kazuhiro Tanaka

Phosphorylations of serines 21/9 in glycogen synthase kinase 3α/β are dispensable for ^V600EBRAF-driven premalignant tumour development in the mouse intestine

Pooyeh Farahmand, Paulina Rzasa, [ ... ], Alessandro Rufini

Characterization of the TREM-1 signaling landscape in human neutrophils

Frederic Ries, Matthias Klein, [ ... ], Markus P. Radsak

Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype

Xuerao Ning, Thảo Thi Thanh Nguyễn, [ ... ], Masatoshi Tagawa

The venom gland transcriptome of Tityus paraguayensis reveals a diverse array of bioactive molecules from the Brazilian Cerrado

Henrique Ranieri Covali-Pontes, Brayhan Meneguelli, [ ... ], Malson Neilson Lucena

TL1A serves as a positive regulator to promote adipocyte differentiation

Ziqi Chang, Qiaoyu Wang, [ ... ], Dan Zhao

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