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Post-translational modification

Electrophysiological evaluation of an anticancer drug gemcitabine on cardiotoxicity revealing down-regulation and modification of the activation gating properties in the human rapid delayed rectifier potassium channel

Mengyan Wei, Pu Wang, [ ... ], Katsushige Ono

The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells

Nadine Bachtler, Sandra Torres, [ ... ], Sabine Klein

Age-related changes in tau and autophagy in human brain in the absence of neurodegeneration

Shreyasi Chatterjee, Megan Sealey, [ ... ], Amritpal Mudher

The Q163C/Q309C mutant of α_MI-domain is an active variant suitable for NMR characterization

Hoa Nguyen, Tianwei Jing, Xu Wang

Stability analysis of a multiscale model of cell cycle dynamics coupled with quiescent and proliferating cell populations

Iqra Batool, Naim Bajcinca

Farnesol and phosphorylation of the transcriptional regulator Efg1 affect Candida albicans white-opaque switching rates

Lucas R. Brenes, Alexander D. Johnson, Matthew B. Lohse

Tramadol regulates the activation of human platelets via Rac but not Rho/Rho-kinase

Hiroki Iida, Takashi Onuma, [ ... ], Haruhiko Tokuda

SHP-1 tyrosine phosphatase binding to c-Src kinase phosphor-dependent conformations: A comparative structural framework

Mehreen Gul, Ahmad Navid, Muhammad Fakhar, Sajid Rashid

Therapeutic effect of ibrutinib, a selective Bruton’s tyrosine kinase inhibitor, in orbital fibroblasts from patients with Graves’ orbitopathy

Hyun Young Park, Min Kyung Chae, [ ... ], Jin Sook Yoon

Scalable agroinfiltration-based production of SARS-CoV-2 antigens for use in diagnostic assays and subunit vaccines

Jordan Demone, Mariam Maltseva, [ ... ], Allyson M. MacLean

Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress

Arini Isnani Preninka, Karen Kuriya, [ ... ], Koichiro Ozawa

Rosetta FlexPepDock to predict peptide-MHC binding: An approach for non-canonical amino acids

Nathaniel Bloodworth, Natália Ruggeri Barbaro, [ ... ], Jens Meiler

Drug resistance mechanisms create targetable proteostatic vulnerabilities in Her2+ breast cancers

Navneet Singh, Lindsey Romick-Rosendale, [ ... ], Kakajan Komurov

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