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Phosphorylation

N-acetyl-L-leucine normalizes Transcription Factor EB activity by stereospecific bidirectional modulation in a HeLa cell model of Niemann-Pick disease type C

Lianne C. Davis, Wim Annaert, Rebecca Braine, Grant C. Churchill, Mallory Factor, Taylor Fields, Marc Patterson, Frances Platt, Dawn Shepherd, Michael Strupp, Antony Galione

published 17 Jul 2026

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A role for nucleosome remodellers during resection of deprotected telomeres in yeast

Anja M. Deiser, Caitlyn Agar, Juan de Dios Barba Tena, Boris Pfander

published 10 Jul 2026

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HIV-1 Nef inhibits the JAK/STAT signaling pathway by inducing proteasomal degradation of STAT1

Roger L. Rodrigues, Mara E. da Silva-Januário, Vinicius B. Apolloni, Constanza E. Espada, Taissa R. Jorge, Lucas A. Tavares, Andreia N. de Carvalho, Juliano P. Souza, Eurico Arruda, Iranaia Assunção-Miranda, Daniel S. Mansur, Luis L. P. daSilva

published 10 Jul 2026

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Compressive stress inhibits proliferation in AsPC-1 pancreatic cancer cells and reduction of Myc protein

Fuko Miyake, Seiichiro Ishihara, Naomi Ando, Shoichiro Tange, Atsushi Enomoto, Hisashi Haga

published 09 Jul 2026

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Inhibition of SUR1-TRPM4 attenuates astrocyte swelling and reactivity under oxygen-glucose deprivation/reoxygenation

Yuanyuan Zhao, Narawut Pakaprot, Rujapope Sutiwisesak, Unchalee Vattarakorn, Sompol Tapechum

published 24 Jun 2026

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Omipalisib reduces hyperphosphorylated tau protein by modulating mTOR-autophagy pathway

Haeun Hwang, Namkwon Kim, Subyn Jeon, Yoojin Lee, Jeongmin Son, Seung Ho Jeon, Yeongae Lee, Min Sung Gee, Kyung-Soo Inn, Jong Kil Lee

published 23 Jun 2026

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Hypergravity reduces F-actin accumulation in osteoclasts, with attenuated bone resorption

Natsuhiro Takahashi, Akihiko Fujita, Yuki Azetsu, Akiko Karakawa, Mie Myers, Masamichi Takami, Masahiro Chatani

published 16 Jun 2026

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THSD7B promotes tumor progression and is associated with prognosis in gastric adenocarcinoma

Xinying Quan, Wei Cheng, Yao Pu, Hong Deng

published 12 Jun 2026

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Single-cell profiling of kinase substrate phosphorylation by single-molecule imaging

Takuya Hidaka, Ryotaro Motoya, Gao Jintian, Sooyeon Kim, Yuichi Taniguchi

published 05 Jun 2026

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Identification of CAND1 as a DNA-dependent protein kinase-regulated coactivator of androgen receptor and the ARv7 splice variant

Ross A. Hamilton, Basil Paul, Ping Yi, Kimal Rajapakshe, Anil K. Panigrahi, Sandra L. Grimm, Cristian Coarfa, Anna Malovannaya, Nancy L. Weigel, David M. Lonard, Charles E. Foulds

published 14 May 2026

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Phosphorylation landscape of dengue virus proteins and their implications in protein-protein interactions

Prakhar Agrawal, Rahul Yadav, Arumugam Madhumalar, Ganesan Senthil Kumar

published 12 May 2026

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DJ-1 alleviates high glucose-induced podocyte injury via activating ERK1/2 signaling

Xiaochen Tian, Jing Li, Tao Han, Leisheng Zhang, Ping Lu, Yusheng Liu

published 17 Apr 2026

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Human resistin is critical to activation of the NLRP3 inflammasome in macrophages

Udeshika Kariyawasam, Winson Lam, John Skinner, Rituparna Chakrabarti, Andrea Cox, Paul M. Hassoun, Qing Lin, Roger A. Johns

published 10 Apr 2026

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