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Pharmacokinetics

Associations of CYP2B6, CYP2C19, and CYP2D6 isoforms and phenoconversion with sertraline pharmacokinetics

Begoña Tapia-Alzuguren, Covadonga Canga-Espina, Patricio Molero, Azucena Aldaz

published 10 Jun 2026

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Isolation of bioactive compounds from the petroleum ether soluble fraction of Eichhornia crassipes (Mart.) Solms flowers with dual evaluation: In silico studies of isolated molecules and in vitro/in vivo activities of the extract

Md. Mirazul Islam, Suriya Akter Shompa, Hasin Hasnat, Safaet Alam, Saima Jahan Riti, Ferdousy Kabir, Md. Sakhawat Hossain, Mohammad A. Rashid

published 08 Jun 2026

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Mapping metabolic reprogramming in lung and breast cancer through integrative bioinformatics

Nosayba Al-Damook, Molham Sakkal, Mostafa Khair, Walaa K. Mousa, Rose Ghemrawi

published 04 Jun 2026

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GPR37 modulates body weight and insulin sensitivity in a sex-biased manner

Mariam Ahmed, Mariela Nunez Santos, Karen Abdelsayed, Corrine Liu, Nimco Xuseen, Pokuaa Adwoa Boakye, Sharon Owino

published 28 May 2026

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Analysis of IMRT patient specific quality assurance using EPID measurement data from the Halcyon linear accelerator

Shinhaeng Cho, Jea-Uk Jeong, Yong Hyub Kim, Mee Sun Yoon, Taek-Keun Nam, Sung-Ja Ahn, Ju-Young Song

published 14 May 2026

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Optimizing breast cancer treatment strategies through fractional-order dynamics: A computational modeling approach

Irshad Sikandar Jamadar, Krishna Kumar, Ambareen Khan, Sher Afghan Khan, Ahmad Aziz Alahmadi, Mamdooh Alwetaishi, Liew Tze Hui

published 14 May 2026

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UBE2S emerges as a key driver in an NK cell–based prognostic model for clear cell renal cell carcinoma

Kang Leng, Yiheng Zhou, Jian Zhao, Xiaoguang Wang, Hua Song

published 14 May 2026

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A pumpless liver-adipose model for studying metabolic dysfunction and drug responses

Zeinab Ebrahimian, Fatemeh Kalalinia, Amir Reza Ameri, Hossein Hosseinzadeh, Bibi Marjan Razavi, Seyed Ali Mousavi Shaegh

published 08 May 2026

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Computational modeling of intravitreal ranibizumab kinetics: Predicting macular drug concentration and half-life

Jabia Mostofa Chowdhury

published 07 May 2026

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In silico evaluation of garlic-derived organosulfur compounds as multi-target inhibitors of breast cancer biomarkers

Courage Siame, Benedict Ofori, Lily Paemka, Kwabena Owusu Danquah

published 06 May 2026

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Machine learning-based unified models for predicting drug clearance from pharmacokinetic animal and study design variables

Remya Ampadi Ramachandran, Lisa A. Tell, Melissa A. Mercer, Xuan Xu, Nuwan Indika Millagaha Gedara, Maaike Ottoline Clapham, Zhoumeng Lin, Jim E. Riviere, Majid Jaberi-Douraki

published 06 May 2026

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Multi-task gradient boosting with multi-modal molecular representations for simultaneous prediction of drug clearance and volume of distribution

Gyu-Seong Lee, Hyeong-Gyu Choi, Dae-Keun Park, Hyo Young Kim

published 29 Apr 2026

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Evaluation of therapeutic efficacy of baloxavir marboxil against high pathogenicity avian influenza virus infection in duck model

Yo Shimazu, Norikazu Isoda, Takahiro Hiono, Yik Lim Hew, Daiki Kobayashi, Misato Shibazaki, Bao Linh Nguyen, Tatsuru Morita, Ryo Daniel Obara, Mariko Miki, Hiromi Osaki, Takao Shishido, Yoshinori Ikenaka, Yoshihiro Sakoda

published 15 Apr 2026

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