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Pharmacokinetics

The identification of metabolites from gut microbiota in HPV infection via network pharmacology

Wenbo Dong, Bai Li, Zhiwei Xu, Qi Wang, Zhihui Hou, Hongling Jia

published 10 Apr 2026

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Ionic-liquid-facilitated transdermal absorption of lidocaine hydrochloride

Xiaoting Ma, Yangzhe Zhou, Ke Jiang, Yuqi Wen

published 03 Apr 2026

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Design and evaluation of a novel expandable gastroretentive film for sustained Metoprolol release

Mustafa Musa Khalaf, Oday Sajad, Rana M. F. Sammour, Bazigha K. Abdul Rasool

published 01 Apr 2026

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Study protocol to establish a prospective cohort for the study of phenotypic clusters, progression pathways, and outcomes of frailty and dependence: The CohorFES

Natàlia Garcia-Giralt, Diana Ovejero, Jose Antonio Carnicero Carreño, Anna Ribes, Pedro Abizanda Soler, Jose Antonio Serra Rexach, Francisco José García García, Montse Rabassa, Leocadio Rodriguez Mañas, Àlex Sanchez Pla, Mariam El Assar de la Fuente, Carmen Maria Osuna Del pozo, Inmaculada Carmona, María Ángeles Caballero-Mora, Virginia Mazoteras Muñoz, Elisa Belen Cortes Zamora, Almudena Avendaño Céspedes, Bárbara Agud Andreu, Fernando Gómez Galera, Jade Soldado-Folgado, Maria Cristina Andrés Lacueva, Xavier Nogués

published 26 Mar 2026

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Assessment of a baloxavir marboxil treatment protocol for high pathogenicity avian influenza in Okinawa Rails, an endangered species endemic to Japan

Mariko Miki, Yo Shimazu, Ryo Daniel Obara, Takashi Nagamine, Yumiko Nakaya, Yoshinori Ikenaka, Hiromi Osaki, Takashi Kimura, Takahiro Hiono, Norikazu Isoda, Takao Shishido, Yoshihiro Sakoda

published 23 Mar 2026

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Mutual solubilization of rosiglitazone and ibuprofen: Investigation and mechanistic insight

Yaxiang Gong, Wenqi Liu

published 18 Mar 2026

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Effect of anticancer activity of aripiprazole main metabolite OPC-14857 on malignant glioblastoma

Shuhei Nakao, Yuki Uemichi, Shuji Nagano, Miyuki Mabuchi, Shiho Ohmori, Daichi Enomoto, Takehiko Ueyama, Tadashi Shimizu

published 13 Mar 2026

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Potentially unsafe doses of local anesthetics in axillary brachial plexus block: A single-center retrospective cohort study

Mélanie Suppan, Caroline Flora Samer, Georges Louis Savoldelli

published 11 Mar 2026

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A prospective observational study of plasma concentrations and safety of combined intravenous lidocaine and epidural ropivacaine in laparotomy surgery

Ottilie Trocheris-Fumery, Alexandre Pruvot, Paul Tarpin, Sophie Collette, Sandra Bodeau, Momar Diouf, Jean-Marc Régimbeau, Hervé Dupont, Stéphane Bar, Youssef Bennis, Osama Abou-Arab

published 06 Mar 2026

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Purification and pharmacokinetic study of gadoxetate isomers for enhanced rabbit liver MR imaging

Yiling Chang, Qilin Li, Man Yi, JiGen Li, Xiaodong Yuan

published 05 Mar 2026

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Computational modeling for rational design of novel phenoxy tacrine derivatives targeting Alzheimer’s disease

Mohamed El Fadili, Mohammed Er-rajy, Somdutt Mujwar, Abdelouahid Samadi, Samir Chtita, Menana Elhallaoui

published 05 Mar 2026

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Clinical outcomes with lower versus conventional dose polymyxin B regimens in dialysis dependent and non-dialysis patients with gram-negative sepsis: A real-world propensity-score matched cohort study

Asha K. Rajan, Vishal Shanbhag, Vijayanarayana Kunhikatta, Ravindra Prabhu Attur, Beven Nelson, Varun Kumar S. G, Souvik Chaudhuri, Girish Thunga

published 04 Mar 2026

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Cheminformatics-driven discovery of natural isoquinoline alkaloid inhibitors of Beta-secretase I for Alzheimer’s management

Iqra Ahmad, Sara Waheed, Bader S. Alotaibi, Sumra Wajid Abbasi, Muhammad Umer Khan, Faiz Ur Rahman, Hanna Dib, Khaled Fahmi Fawy, Umar Nishan, Abid Ali, Aqal Zaman, Mohibullah Shah

published 02 Mar 2026

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