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Drug metabolism

Orchestration of kaempferol nuclear translocation by phase ii metabolic enzymes and efflux transporters suppresses colorectal cancer

Chishun Zhou, Qing Ning, [ ... ], Linlin Lu

Ketogenic diet–induced changes in hepatic drug metabolism with potential implications for ozanimod pharmacokinetics in mice

Veronika Frybortova, Stefan Satka, [ ... ], Eva Anzenbacherova

Transcriptome analysis of hepatopancreas of Litopenaeus vannamei after acute exposure to Alexandrium pacificum

Fuyuan Zeng, Haiming Chen, [ ... ], Yulei Zhang

Pharmacokinetic barriers to oxfendazole flukicidal efficacy

Laura Ceballos, Candela Canton, [ ... ], Luis Alvarez

Pharmacogenomic landscape in Thailand: Array-based profiling and EMR-linked medication exposure

Phongthana Pasookhush, Sophida Suta, [ ... ], Korapat Mayurasakorn

Computational and experimental evaluation of Pisolithus arhizus metabolites targeting major efflux pumps of mastitis-associated Staphylococcus aureus

Hansa Gul, Iram Zahra, [ ... ], Lennin Garrido-Palazuelos

Key targets and mechanisms by which gut microbiota-derived metabolites regulate Alzheimer’s disease through the immune - inflammatory pathway: Based on network pharmacology and molecular docking

Lei Miao, Fengwei Hou, Guanghong Li

Associations of CYP2B6, CYP2C19, and CYP2D6 isoforms and phenoconversion with sertraline pharmacokinetics

Begoña Tapia-Alzuguren, Covadonga Canga-Espina, Patricio Molero, Azucena Aldaz

Mapping metabolic reprogramming in lung and breast cancer through integrative bioinformatics

Nosayba Al-Damook, Molham Sakkal, [ ... ], Rose Ghemrawi

GPR37 modulates body weight and insulin sensitivity in a sex-biased manner

Mariam Ahmed, Mariela Nunez Santos, [ ... ], Sharon Owino

A pumpless liver-adipose model for studying metabolic dysfunction and drug responses

Zeinab Ebrahimian, Fatemeh Kalalinia, [ ... ], Seyed Ali Mousavi Shaegh

Higher order synthetic lethals are keys to minimize cancer treatment effects on non-tumor cells

Mehdi Dehghan Manshadi, Payam Setoodeh, [ ... ], Habil Zare

The identification of metabolites from gut microbiota in HPV infection via network pharmacology

Wenbo Dong, Bai Li, [ ... ], Hongling Jia

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