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Drug metabolism

Higher order synthetic lethals are keys to minimize cancer treatment effects on non-tumor cells

Mehdi Dehghan Manshadi, Payam Setoodeh, [ ... ], Habil Zare

The identification of metabolites from gut microbiota in HPV infection via network pharmacology

Wenbo Dong, Bai Li, [ ... ], Hongling Jia

Study protocol to establish a prospective cohort for the study of phenotypic clusters, progression pathways, and outcomes of frailty and dependence: The CohorFES

Natàlia Garcia-Giralt, Diana Ovejero, [ ... ], Xavier Nogués

Effect of anticancer activity of aripiprazole main metabolite OPC-14857 on malignant glioblastoma

Shuhei Nakao, Yuki Uemichi, [ ... ], Tadashi Shimizu

Potentially unsafe doses of local anesthetics in axillary brachial plexus block: A single-center retrospective cohort study

Mélanie Suppan, Caroline Flora Samer, Georges Louis Savoldelli

Effects of tacrolimus treatment on the gut microbiota and metabolites in liver transplant recipients

Guohui Wang, Lu Liu, [ ... ], Cangsang Song

Nontargeted metabolomics analysis of potential biomarkers for patients with chronic ischemic stroke in extremely cold rural regions: An exploratory case-control study

Li Bai, Zhongyuan Li, [ ... ], Hong Chao

Coupled pharmacokinetic model unveils drug-drug interactions in plasma concentration

Hong Huang, Chaoyang Li, [ ... ], Xiaohong Li

Identifying optimal combination regimens for therapy of Mycobacterium tuberculosis with an algorithmic approach: prospective predictions and validations

Arnold Louie, Michael Neely, [ ... ], George Drusano

Clinical and metabolic profile of adults with obesity attending lifestyle medicine clinics

Hanan N. AlTaib, Reem AlAqeel, [ ... ], Haifa F. AlOtaibi

Pharmacokinetics of Dolutegravir, nucleoside analogues, and intracellular metabolites using plasma separation cards: A comparative analysis with traditional sampling methods in healthy volunteers

Beth Thompson, Laura J. Else, [ ... ], Rhonda M. Brand

Comparison of self-reported survey and wastewater-based epidemiology measures of cocaine use on a college campus

Shona McCulloch, Dessa Bergen-Cico, Teng Zeng, David A. Larsen

Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity

Chizuka Obara, Yohei Iizaka, [ ... ], Shinpei Yamaguchi

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