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Drug metabolism

Nontargeted metabolomics analysis of potential biomarkers for patients with chronic ischemic stroke in extremely cold rural regions: An exploratory case-control study

Li Bai, Zhongyuan Li, [ ... ], Hong Chao

Coupled pharmacokinetic model unveils drug-drug interactions in plasma concentration

Hong Huang, Chaoyang Li, [ ... ], Xiaohong Li

Identifying optimal combination regimens for therapy of Mycobacterium tuberculosis with an algorithmic approach: prospective predictions and validations

Arnold Louie, Michael Neely, [ ... ], George Drusano

Clinical and metabolic profile of adults with obesity attending lifestyle medicine clinics

Hanan N. AlTaib, Reem AlAqeel, [ ... ], Haifa F. AlOtaibi

Pharmacokinetics of Dolutegravir, nucleoside analogues, and intracellular metabolites using plasma separation cards: A comparative analysis with traditional sampling methods in healthy volunteers

Beth Thompson, Laura J. Else, [ ... ], Rhonda M. Brand

Comparison of self-reported survey and wastewater-based epidemiology measures of cocaine use on a college campus

Shona McCulloch, Dessa Bergen-Cico, Teng Zeng, David A. Larsen

Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity

Chizuka Obara, Yohei Iizaka, [ ... ], Shinpei Yamaguchi

Bioactive fungal metabolites as SIRT2 antagonists: A computational quest for cancer treatment

Md. Habib Ullah Masum, Syed Mohammad Lokman, [ ... ], Ahmad Abdullah Mahdeen

A novel prognostic model for lung squamous cell carcinoma based on multi-omics analysis and machine learning

Jian Li, Zengqiang Shen, Dabei Liu, Jun Ma

Impacts of polymorphisms in drug-metabolizing enzyme and transporter genes on irinotecan toxicity and efficacy in Thai colorectal cancer patients

Natthakul Akarapredee, Chalirmporn Atasilp, [ ... ], Natchaya Vanwong

Mass spectrometry-based metabolomics uncovers distinct metabolic signatures and potential therapeutic targets in Plasmodium knowlesi

Naphatsamon Uthailak, Sadudee Chotirat, [ ... ], Onrapak Reamtong

Optimizing blood alcohol concentration measurement with breath alcohol meter and its preliminary application in evaluating CYP2E1 activity

Jiayi Zhang, Yingqi Hu, [ ... ], Yongzhi Xue

Circulating metabolites in patients with chronic heart failure are not related to gut leakage or gut dysbiosis

Andraž Nendl, Sajan C. Raju, [ ... ], Ayodeji Awoyemi

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