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Drug metabolism

Effect of anticancer activity of aripiprazole main metabolite OPC-14857 on malignant glioblastoma

Shuhei Nakao, Yuki Uemichi, [ ... ], Tadashi Shimizu

Potentially unsafe doses of local anesthetics in axillary brachial plexus block: A single-center retrospective cohort study

Mélanie Suppan, Caroline Flora Samer, Georges Louis Savoldelli

Effects of tacrolimus treatment on the gut microbiota and metabolites in liver transplant recipients

Guohui Wang, Lu Liu, [ ... ], Cangsang Song

Nontargeted metabolomics analysis of potential biomarkers for patients with chronic ischemic stroke in extremely cold rural regions: An exploratory case-control study

Li Bai, Zhongyuan Li, [ ... ], Hong Chao

Coupled pharmacokinetic model unveils drug-drug interactions in plasma concentration

Hong Huang, Chaoyang Li, [ ... ], Xiaohong Li

Identifying optimal combination regimens for therapy of Mycobacterium tuberculosis with an algorithmic approach: prospective predictions and validations

Arnold Louie, Michael Neely, [ ... ], George Drusano

Clinical and metabolic profile of adults with obesity attending lifestyle medicine clinics

Hanan N. AlTaib, Reem AlAqeel, [ ... ], Haifa F. AlOtaibi

Pharmacokinetics of Dolutegravir, nucleoside analogues, and intracellular metabolites using plasma separation cards: A comparative analysis with traditional sampling methods in healthy volunteers

Beth Thompson, Laura J. Else, [ ... ], Rhonda M. Brand

Comparison of self-reported survey and wastewater-based epidemiology measures of cocaine use on a college campus

Shona McCulloch, Dessa Bergen-Cico, Teng Zeng, David A. Larsen

Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity

Chizuka Obara, Yohei Iizaka, [ ... ], Shinpei Yamaguchi

Bioactive fungal metabolites as SIRT2 antagonists: A computational quest for cancer treatment

Md. Habib Ullah Masum, Syed Mohammad Lokman, [ ... ], Ahmad Abdullah Mahdeen

A novel prognostic model for lung squamous cell carcinoma based on multi-omics analysis and machine learning

Jian Li, Zengqiang Shen, Dabei Liu, Jun Ma

Impacts of polymorphisms in drug-metabolizing enzyme and transporter genes on irinotecan toxicity and efficacy in Thai colorectal cancer patients

Natthakul Akarapredee, Chalirmporn Atasilp, [ ... ], Natchaya Vanwong

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