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Partial agonists

Descriptive molecular pharmacology of the δ opioid receptor (DOR): A computational study with structural approach

Guillermo Goode-Romero, Laura Dominguez

Reflected generalized concentration addition and Bayesian hierarchical models to improve chemical mixture prediction

Daniel Zilber, Kyle Messier

Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics

Richard L. Cullum, Lauren M. Lucas, [ ... ], David J. Riese, II

Dual inhibitory action of trazodone on dorsal raphe serotonergic neurons through 5-HT_1A receptor partial agonism and α₁-adrenoceptor antagonism

Alberto Montalbano, Boris Mlinar, [ ... ], Renato Corradetti

Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids

Keith M. Olson, David I. Duron, [ ... ], John M. Streicher

5-HT₂ receptor binding, functional activity and selectivity in N-benzyltryptamines

Miguel Toro-Sazo, José Brea, [ ... ], Bruce K. Cassels

NOP receptor pharmacological profile – A dynamic mass redistribution study

Davide Malfacini, Katharina Simon, [ ... ], Girolamo Calo’

GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent

Michele J. Pachanski, Melissa E. Kirkland, [ ... ], Maria E. Trujillo

Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders

Bitna Yi, Alam Jahangir, [ ... ], Mehrdad Shamloo

GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production

Corin Miller, Michele J. Pachanski, [ ... ], Maria E. Trujillo

Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPARγ partial agonists

Katrine Qvortrup, Jakob F. Jensen, [ ... ], Thomas E. Nielsen

Ligand Binding at the α4-α4 Agonist-Binding Site of the α4β2 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State

Dinesh C. Indurthi, Trevor M. Lewis, [ ... ], Nathan L. Absalom

Investigating the Role of Loop C Hydrophilic Residue ‘T244’ in the Binding Site of ρ1 GABA_C Receptors via Site Mutation and Partial Agonism

Moawiah M. Naffaa, Nathan Absalom, [ ... ], Jane R. Hanrahan

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