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Organoids

A comparative study of organoid-derived and cell line-derived intestinal epithelial models

Melis Asal, Nanne J. Paauw, Hetty J. Bontkes, Sandra J. van Vliet, Reina E. Mebius, Susan Gibbs

published 16 Apr 2026

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Biobanking of gynecologic cancer biospecimens: Development, quality control, and translational applications

Jue Young Kim, Yoo-Kyung Lee, Ha-Yeon Shin, Yoon Joo Kim, Mi Ae Jeon, Wookyeom Yang, Anna Jun, Kyungmin Kim, Hanbyoul Cho, Min-A Kim, Jae-Hoon Kim

published 31 Mar 2026

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Patient-derived organoids predict chemotherapy response of locally advanced gastric cancer

Miao Huang, Jiahui Chu, Wenbin Yu, Liliang Dou, Qiushi Wang, Fan Jiang, Meng Wei, Xiaohan Cui, Wen Zhao, Jianyuan Zhou, Song Li, Lian Liu

published 09 Mar 2026

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Wnt/β-catenin signalling modulates the timing of cell fate decision making in the early mouse embryo

Joaquin Lilao-Garzón, Elena Corujo-Simon, Meritxell Vinyoles, Sabine C. Fischer, José Guillén, Tina Balayo, Silvia Muñoz-Descalzo

published 06 Mar 2026

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Taurocholic acid induces intrahepatic cholangiocyte cell proliferation via activating NRAS and YAP1

Lum Fube, Arul Thason, Elizabeth Taliaferro, Carol Heckman, Surya Amarachintha

published 04 Feb 2026

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DNA methylation-driven gene-based drug response prediction model for liver cancer: The critical role of GLS

Shuang Zheng, Xi Yu, Xiaozhou Wang, Yi Ma, Yujia Han, Jing Zhang, Wei Wu, Chunyu Sun, Lijie He

published 05 Dec 2025

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Establishment and culture of mouse oviductal organoids and isolation and characterization of their secreted extracellular vesicles

Riley E. Thompson-Brandhagen, Mindy A. Meyers, Richard B. McCosh, Fiona K. Hollinshead

published 04 Dec 2025

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Matrix stiffness influences drug resistance to gemcitabine analog and AZD 1775 combination in PDAC organoids

Jonathan Barajas, Zhi Yang, Edward Agyare, Xueyou Zhu, Saun-Joo Yoon, Bo Han

published 04 Dec 2025

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Synergistic enhancement of AAV gene delivery in 2D cells and 3D organoids using polybrene and hydroxychloroquine

Hyeon-Jin Na, Yongbo Shin, Seung-Hyun Kim, Seung Pil Jang, Myung Jin Son, Yong Min Choi, Hyeon Gyeol Jeon, Ok-Seon Kwon, Kyung-Sook Chung

published 14 Nov 2025

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STAG2 mutations in the normal colon induce upregulation of oncogenic pathways in neighbouring wildtype cells

Wei Ni Yew, Christopher James Dean, Dedrick Kok Hong Chan

published 15 Oct 2025

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Flow cytometry protocol for cell death analysis in glioblastoma organoids: A technical note

Anna-Laura Potthoff, Meng-Chun Hsieh, Ahmad Melhem, Susanna S. Ng, Barbara E. F. Pregler, Annika Vieregge, Markus Raspe, Lea L. Friker, Thomas Zeyen, Julian P. Layer, Andreas Dolf, Marieta I. Toma, Andreas Waha, Torsten Pietsch, Mike-Andrew Westhoff, Hartmut Vatter, Michael Hölzel, Ulrich Herrlinger, Matthias Schneider

published 23 Sep 2025

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Enhanced electrophysiological recordings in acute brain slices, spheroids, and organoids using 3D high-density multielectrode arrays

Lisa Mapelli, Danila Di Domenico, Giacomo Sciacca, Francesco Mainardi, Alessandra Ottaviani, Anita Monteverdi, Mariateresa Tedesco, Chiara Rosa Battaglia, Simona Tritto, Mauro Gandolfo, Kilian Imfeld, Stefanie Kiderlen, Lukas Krainer, Chiara Cervetto, Manuela Marcoli, Anson Sing, Jimena Andersen, Fikri Birey, Steven A. Sloan, Alessandro Maccione, Egidio D'Angelo

published 04 Sep 2025

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Precision-cut tumor tissue slices, a novel tool to study the tumor microenvironment interactions with chimeric antigen receptor (CAR) T cells

Valeria Durante, Alina Wittwer, Benjamin Theek, Manuel Martinez-Osuna, Emmanuel Donnadieu, Olaf Hardt, Dominik Eckardt, Andreas Bosio, Sonja Schallenberg, Christoph Herbel

published 08 Aug 2025

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