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Organoids

Taurocholic acid induces intrahepatic cholangiocyte cell proliferation via activating NRAS and YAP1

Lum Fube, Arul Thason, Elizabeth Taliaferro, Carol Heckman, Surya Amarachintha

published 04 Feb 2026

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DNA methylation-driven gene-based drug response prediction model for liver cancer: The critical role of GLS

Shuang Zheng, Xi Yu, Xiaozhou Wang, Yi Ma, Yujia Han, Jing Zhang, Wei Wu, Chunyu Sun, Lijie He

published 05 Dec 2025

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Establishment and culture of mouse oviductal organoids and isolation and characterization of their secreted extracellular vesicles

Riley E. Thompson-Brandhagen, Mindy A. Meyers, Richard B. McCosh, Fiona K. Hollinshead

published 04 Dec 2025

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Matrix stiffness influences drug resistance to gemcitabine analog and AZD 1775 combination in PDAC organoids

Jonathan Barajas, Zhi Yang, Edward Agyare, Xueyou Zhu, Saun-Joo Yoon, Bo Han

published 04 Dec 2025

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Synergistic enhancement of AAV gene delivery in 2D cells and 3D organoids using polybrene and hydroxychloroquine

Hyeon-Jin Na, Yongbo Shin, Seung-Hyun Kim, Seung Pil Jang, Myung Jin Son, Yong Min Choi, Hyeon Gyeol Jeon, Ok-Seon Kwon, Kyung-Sook Chung

published 14 Nov 2025

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STAG2 mutations in the normal colon induce upregulation of oncogenic pathways in neighbouring wildtype cells

Wei Ni Yew, Christopher James Dean, Dedrick Kok Hong Chan

published 15 Oct 2025

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Flow cytometry protocol for cell death analysis in glioblastoma organoids: A technical note

Anna-Laura Potthoff, Meng-Chun Hsieh, Ahmad Melhem, Susanna S. Ng, Barbara E. F. Pregler, Annika Vieregge, Markus Raspe, Lea L. Friker, Thomas Zeyen, Julian P. Layer, Andreas Dolf, Marieta I. Toma, Andreas Waha, Torsten Pietsch, Mike-Andrew Westhoff, Hartmut Vatter, Michael Hölzel, Ulrich Herrlinger, Matthias Schneider

published 23 Sep 2025

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Enhanced electrophysiological recordings in acute brain slices, spheroids, and organoids using 3D high-density multielectrode arrays

Lisa Mapelli, Danila Di Domenico, Giacomo Sciacca, Francesco Mainardi, Alessandra Ottaviani, Anita Monteverdi, Mariateresa Tedesco, Chiara Rosa Battaglia, Simona Tritto, Mauro Gandolfo, Kilian Imfeld, Stefanie Kiderlen, Lukas Krainer, Chiara Cervetto, Manuela Marcoli, Anson Sing, Jimena Andersen, Fikri Birey, Steven A. Sloan, Alessandro Maccione, Egidio D'Angelo

published 04 Sep 2025

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Precision-cut tumor tissue slices, a novel tool to study the tumor microenvironment interactions with chimeric antigen receptor (CAR) T cells

Valeria Durante, Alina Wittwer, Benjamin Theek, Manuel Martinez-Osuna, Emmanuel Donnadieu, Olaf Hardt, Dominik Eckardt, Andreas Bosio, Sonja Schallenberg, Christoph Herbel

published 08 Aug 2025

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Development of a tissue-specific bioscaffold for intestinal stem cell culture

Sachin Kakar, Mathieu F. Derouet, Liyue Zhang, Connor J. Gillis, Frederikke Larsen, Arghya Paul, Lauren E. Flynn, Samuel Asfaha

published 06 Aug 2025

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Development and characterization of a 2D porcine colonic organoid model for studying intestinal physiology and barrier function

Masina Plenge, Nadine Schnepel, Mathias Müsken, Judith Rohde, Ralph Goethe, Gerhard Breves, Gemma Mazzuoli-Weber, Pascal Benz

published 07 May 2025

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Digital PCR characterizes epithelial cell populations in murine duodenal organoids

Karla Acosta-Virgen, Hugo David González-Conchillos, Gabriela Vallejo-Flores, Lizbeth Iliana Salazar-Villatoro, Ernesto Guerrero-Sánchez, Adolfo Martínez-Palomo, Martha Espinosa-Cantellano

published 13 Mar 2025

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zIncubascope: Long-term quantitative imaging of multi-cellular assemblies inside an incubator

Anirban Jana, Naveen Mekhileri, Adeline Boyreau, Aymerick Bazin, Nadège Pujol, Kevin Alessandri, Gaëlle Recher, Pierre Nassoy, Amaury Badon

published 23 Jan 2025

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