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Nucleic acids

Good DNA- and sufficient RNA integrity in formalin-free paraffin-embedded tissues

Maarten Niemantsverdriet, Natalie Methorst, Sanne Yvet Hoek, Ageeth Knol, Agnes Marije Hoogland

published 14 Aug 2026

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Prediction of potential biomarkers and therapeutic targets in HIV viremic patients using immune-related circRNA-miRNA-mRNA regulatory networks

Negin Faraji, Leila Rouhi, Azam Bolhassani, Behnam Hasannejad-asl, Kazem Baesi, Ladan Abbasian

published 14 Aug 2026

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A chemically optimized, GalNAc-conjugated siRNA targeting HSD17B13 demonstrates efficacy in a human 3D organoid model of MASH, showcasing an alternative to animal testing

Qin Meng, Xujia Wang, Yuxuan Zhang, Sudeep Pushpakom, Jun Yang, Hui Feng, Mu Wang

published 14 Aug 2026

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Study protocol: Effect of inulin supplementation on gut microbiota in patients with oral lichen planus — A double-blind, randomised, placebo-controlled parallel-group trial

Koki Nambu, Naoki Kaneko, Shiho Yokomizo, Hu Chen, Lijing Yan, Wang Shiyao, Ryusei Shizuma, Eiji Iwata, Yukiko Ohyama, Shohei Akagawa, Soichiro Ibaragi, Shintaro Kawano, Masafumi Moriyama

published 13 Aug 2026

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CLR-Seq: A pipeline to identify bacterial microbiota species with immune-relevant glycan moieties through human C-type lectin receptor interaction

Jasper Mol, Rob van Dalen, Yvonne Pannekoek, Malgorzata E. Mnich, Marcel R. de Zoete, Mark Davids, Hilde Herrema, Nina M. van Sorge

published 13 Aug 2026

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Optimization of the Mit1C real-time PCR assay using Bio-Rad CFX96 for the detection of Cyclospora cayetanensis in agricultural waters

Khai Truong, Miely Suarez, Mauricio Durigan, Laura Ewing-Peeples, Mark C. Jenkins, Aminata Kilungo, Margarethe A. Cooper, Kerry K. Cooper, Gerardo U. Lopez

published 12 Aug 2026

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Targeting telomeres in brain vasculature does not impede initiation and progression of glioblastoma

Amparo Sánchez-Hernández, Sonia Burgaz, Jessica Louzame-Ruano, Óscar Laguía, Giuseppe Bosso, Rosa Serrano, Ana Cayuela López, Juana María Flores, Paula Martínez, Maria A. Blasco

published 12 Aug 2026

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A comparative study of CDO1 promoter methylation in gastric cancer and H. pylori-associated chronic gastritis: Implications for diagnostic performance

Selin Kankaya, Metehan Karatas, Engin Hatipoglu, Nuray Kepil, Zulal Kaptan, Zeynep Caliskan, Matem Tuncdemir, Yildiz Dincer

published 12 Aug 2026

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Genomic epidemiology of multidrug-resistant and ESBL-producing Proteus mirabilis in a military referral hospital in Ethiopia

Yacob Mohammed Yusuf, Adey Feleke Desta, Desta Ayana, Helen Nigussie Aychegrew, Rajiha Abubeker, Biruk Samson, Tolewak Sura, Atsbeha Gebreegziabxier, Abebe Asseffa Negeri, Chala Bashea, Melak Getu, Gebremedhin Gebremichael, Amete Mihret, Eleni Kidane, Ebisa Mezgebu, Sami Sebri, Gemechu Tadesse, Getachew Tollera, Abraham Ali, Gurja Belay Woldemichael

published 11 Aug 2026

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Exploring the Role of Nesprin1 in isoproterenol-induced heart failure: Insights into pathogenesis and therapeutic implications

Qin Qin, Cenyuan Dong, Ziyi Zhou, Yangyuanzhi Liu, Mengpan Liu, Chunyu Cao, Lin Teng

published 11 Aug 2026

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Dual regulatory mechanisms of YGP1 expression in response to glucose availability in Saccharomyces cerevisiae

Megumi Sato, Kaoru Irie, Yasuyuki Suda, Tomoaki Mizuno, Kenji Irie

published 07 Aug 2026

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Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection

Elena V. Galitsyna, Anastasiia A. Buianova, Tatiana B. Bukharova, Irina A. Krivosheeva, Mikhail Yu. Skoblov, Dmitriy V. Goldshtein

published 07 Aug 2026

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SEGUID v2: Extending SEGUID checksums for circular, linear, single- and double-stranded biological sequences

Humberto Pereira, Paulo César Silva, M. Wayne Davis, Louis Abraham, György Babnigg, Henrik Bengtsson, Björn Johansson

published 07 Aug 2026

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