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Nucleases

Impact of preanalytical variables on urinary cell-free DNA quality: Centrifugation, EDTA concentration, storage and thawing strategies

Wenjing Li, Shan Guo, Zongning Zhou, Hongwei Peng, Yan Fu, Cong Zou, Xin Zhang, Shenjuan Li, Zhangyan Zhou, Kaiyu Qian, Shanshan Zhang

published 27 Aug 2026

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Diagnostic agreement between Rhinoswabs and joint nose and throat swabs for the detection of influenza and SARS-CoV-2 among symptomatic ambulatory patients in Hong Kong

Caitriona Murphy, Samuel M. S. Cheng, Loretta Mak, Hau Chi So, Dennis K. M. Ip, Malik Peiris, Benjamin J. Cowling

published 11 Aug 2026

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Functional comparison of SP6 RNA polymerase and T7 RNA polymerase

Julia Gutbrod, Svenja Hehn, Antonia Bangnowski, Eleanor Fritz, Andreas Marx

published 22 Jun 2026

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Temporal transcriptomic profiling of pulmonary thromboembolism reveals persistent NETosis- and ferroptosis-associated gene signatures and enhanced thrombolysis with adjunctive DNase I

Jialun Chen, Lingshan Chao, Siqin Han, Zaixing Jia, Weihua Chen, Zhenwei Liu, Jingwen Li, Xixin Yan

published 29 May 2026

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Benchmarking free energy calculations: Analysis of single and double mutations across two simulation software platforms for two protein systems

Shivani Gupta, Qinfang Sun, Ronald M. Levy

published 03 Apr 2026

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In vitro culture of human-infecting Encephalitozoon spp. for genome sequencing with minimal host contaminant

Anne Caroline Mascarenhas dos Santos, Pingdong Liang, Oscar X. Juárez, Jean-François Pombert, Karina Tuz

published 11 Mar 2026

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How much genetic information in RNA form can be protected by a CCMV virus-like particle?

Ana Luisa Duran Meza, Sophie-Christine Porak, Abigail Chapman, Charles M. Knobler, William M. Gelbart

published 10 Dec 2025

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Low level of plasma DNase is associated with worse clinical outcome in testicular germ cell tumor patients and exogeneous DNase I improves cisplatin treatment efficacy

Michal Mego, Barbora Vlkova, Katarina Kalavska, Michal Pastorek, Zuzana Cierna, Zuzana Sestakova, Miroslav Chovanec, Natalia Udvorkova, Lucia Kucerova, Peter Celec

published 04 Dec 2025

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Synergistic enhancement of AAV gene delivery in 2D cells and 3D organoids using polybrene and hydroxychloroquine

Hyeon-Jin Na, Yongbo Shin, Seung-Hyun Kim, Seung Pil Jang, Myung Jin Son, Yong Min Choi, Hyeon Gyeol Jeon, Ok-Seon Kwon, Kyung-Sook Chung

published 14 Nov 2025

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Predicting chromatin conformation contact maps

Alan Min, Jacob Schreiber, Anshul Kundaje, William S. Noble

published 29 Sep 2025

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Deciphering the role of the lncRNA TRIBAL in hepatocyte models

Sébastien Soubeyrand, Paulina Lau, Ruth McPherson

published 02 Sep 2025

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Off-target sequence variations driven by the intrinsic properties of the Cas–sgRNA–DNA complex in genome editing

Celine Kurniawan, Takeshi Itoh

published 18 Jul 2025

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Conserved domains and structural motifs that differentiate closely related Rex1 and Rex3 DEDDh exoribonucleases are required for their function in yeast

Peter W. Daniels, Sophie Kelly, Iwan J. Tebbs, Phil Mitchell

published 02 Jun 2025

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