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Nucleases

How much genetic information in RNA form can be protected by a CCMV virus-like particle?

Ana Luisa Duran Meza, Sophie-Christine Porak, Abigail Chapman, Charles M. Knobler, William M. Gelbart

published 10 Dec 2025

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Low level of plasma DNase is associated with worse clinical outcome in testicular germ cell tumor patients and exogeneous DNase I improves (Leverages) cisplatin treatment efficacy

Mego Michal, Vlkova Barbora, Kalavska Katarina, Pastorek Michal, Cierna Zuzana, Sestakova Zuzana, Chovanec Miroslav, Udvorkova Natalia, Kucerova Lucia, Celec Peter

published 04 Dec 2025

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Synergistic enhancement of AAV gene delivery in 2D cells and 3D organoids using polybrene and hydroxychloroquine

Hyeon-Jin Na, Yongbo Shin, Seung-Hyun Kim, Seung Pil Jang, Myung Jin Son, Yong Min Choi, Hyeon Gyeol Jeon, Ok-Seon Kwon, Kyung-Sook Chung

published 14 Nov 2025

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Predicting chromatin conformation contact maps

Alan Min, Jacob Schreiber, Anshul Kundaje, William S. Noble

published 29 Sep 2025

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Deciphering the role of the lncRNA TRIBAL in hepatocyte models

Sébastien Soubeyrand, Paulina Lau, Ruth McPherson

published 02 Sep 2025

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Off-target sequence variations driven by the intrinsic properties of the Cas–sgRNA–DNA complex in genome editing

Celine Kurniawan, Takeshi Itoh

published 18 Jul 2025

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Conserved domains and structural motifs that differentiate closely related Rex1 and Rex3 DEDDh exoribonucleases are required for their function in yeast

Peter W. Daniels, Sophie Kelly, Iwan J. Tebbs, Phil Mitchell

published 02 Jun 2025

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Different results despite high homology: Comparative expression of human and murine DNase1 in Pichia pastoris

Jan-Ole Krischek, Hans Georg Mannherz, Markus Napirei

published 29 Apr 2025

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Optimized CUT&RUN protocol for activated primary mouse B cells

Stormy E. Ruiz, Robert W. Maul, Patricia J. Gearhart

published 24 Apr 2025

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Onion pollenkitt: Function, DNase activity, fatty acid composition, and SEM imaging

Majd Mardini, Aleksey Ermolaev, Alexey Yu. Kuznetsov, Alexey V. Zhevnerov, Sergey Buravkov, Ludmila Khrustaleva

published 07 Apr 2025

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An SDS-NaOH-based method to isolate genome of recombinant adeno-associated virus vectors for physical titer measurement

Xiangying Zhu, Keying Yang, Jinyan Xie, Xilin Feng, Tao Wu, Mengjun Hu, Haijian Wang, Chenghui Yu, Xiaomin Yu, Farhid Hemmatzadeh, Liqing Zhu, Linhua Zhang

published 03 Apr 2025

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Chemical nucleases are a robust alternative for RNase H cleavage of human ribosomal RNA

Hagen Wesseling, Dennis Krug, Marvin Wehrheim, Michael W. Göbel, Stefanie Kaiser

published 24 Feb 2025

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Differential impact of divalent metals on native elongating transcript sequencing (NET-seq) protocols for RNA polymerases I and II

Abigail K. Huffines, David A. Schneider

published 13 Feb 2025

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