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Nucleases

Functional comparison of SP6 RNA polymerase and T7 RNA polymerase

Julia Gutbrod, Svenja Hehn, [ ... ], Andreas Marx

Temporal transcriptomic profiling of pulmonary thromboembolism reveals persistent NETosis- and ferroptosis-associated gene signatures and enhanced thrombolysis with adjunctive DNase I

Jialun Chen, Lingshan Chao, [ ... ], Xixin Yan

Benchmarking free energy calculations: Analysis of single and double mutations across two simulation software platforms for two protein systems

Shivani Gupta, Qinfang Sun, Ronald M. Levy

In vitro culture of human-infecting Encephalitozoon spp. for genome sequencing with minimal host contaminant

Anne Caroline Mascarenhas dos Santos, Pingdong Liang, [ ... ], Karina Tuz

How much genetic information in RNA form can be protected by a CCMV virus-like particle?

Ana Luisa Duran Meza, Sophie-Christine Porak, [ ... ], William M. Gelbart

Low level of plasma DNase is associated with worse clinical outcome in testicular germ cell tumor patients and exogeneous DNase I improves cisplatin treatment efficacy

Michal Mego, Barbora Vlkova, [ ... ], Peter Celec

Synergistic enhancement of AAV gene delivery in 2D cells and 3D organoids using polybrene and hydroxychloroquine

Hyeon-Jin Na, Yongbo Shin, [ ... ], Kyung-Sook Chung

Predicting chromatin conformation contact maps

Alan Min, Jacob Schreiber, Anshul Kundaje, William S. Noble

Deciphering the role of the lncRNA TRIBAL in hepatocyte models

Sébastien Soubeyrand, Paulina Lau, Ruth McPherson

Off-target sequence variations driven by the intrinsic properties of the Cas–sgRNA–DNA complex in genome editing

Celine Kurniawan, Takeshi Itoh

Conserved domains and structural motifs that differentiate closely related Rex1 and Rex3 DEDDh exoribonucleases are required for their function in yeast

Peter W. Daniels, Sophie Kelly, Iwan J. Tebbs, Phil Mitchell

Different results despite high homology: Comparative expression of human and murine DNase1 in Pichia pastoris

Jan-Ole Krischek, Hans Georg Mannherz, Markus Napirei

Optimized CUT&RUN protocol for activated primary mouse B cells

Stormy E. Ruiz, Robert W. Maul, Patricia J. Gearhart

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