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MAPK signaling cascades

In-silico target prediction and pathway analysis of propranolol as a potential therapeutic agent for hepatocellular carcinoma

Ishaq Ahmad, Shakeel Ahmad Khan, Muhammad Abu Bakar, Adnan Shakoor, Abdul Wasy Zia

published 13 Feb 2026

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Formononetin ameliorates SP-induced urticaria in mice via suppressing TAK1/MAK signaling pathway

Yan Wu, Chunyu Li

published 23 Jan 2026

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Inhibition of HER2 signaling and breast cancer cell growth with a novel antibody targeting HER2 ECD III/IV

Chunchun Liu, Yulei Ren, Xuan Luo, Peiyun Zhou, Xiangjuan Du, Qianmin Wang, Xue Han, Yanhui Xu, Ping Wang, Dan Zhao, Huirong Yang

published 15 Jan 2026

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Upregulation of angiotensin-(1–7) formation in human podocytes – enzyme activity assay upon fluid flow shear stress

Debora Kaiser-Graf, Oliver Domenig, Marko Poglitsch, Reinhold Kreutz, Juliane Bolbrinker

published 09 Jan 2026

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Fine mapping and transcriptomics reveal OSG function in regulation of grain size and pollen fertility in rice (Oryza sativa)

Sijie Zhao, Siyue Zhang, Weichen Xu, Sijia Fang, Mei Liu, Lei Wang, Xianyang Zhang, Bingxu Chen, Shuya Wei, Heming Zhao

published 08 Jan 2026

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Effect of exercise preconditioning on myocardial content of Sphingosine1-phosphate and its mechanism in rats after exhaustive exercise

Xinnuan Wei, Weiyuan Yang, Junxiang Zhou, Luoyuan Cao, Wenxing Jiang

published 07 Jan 2026

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Identification of PANoptosis-associated genes in hepatic ischemia-reperfusion injury by integrated bioinformatics analysis and machine learning

Alimu Tulahong, Xinlu Xu, Aimitaji Abulaiti, Talaiti Tuergan, Pingping Qiao, Dalong Zhu, Chang Liu, Rexiati Ruze, Tuerganaili Aji, Yingmei Shao

published 30 Dec 2025

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MicroRNA mediated regulation in early-onset cardiac hypertrophy: Insights from the hypertrophic heart rat model

Shahzad Sadiq, Fadi J. Charchar, Andrew Sanigorski, Tamsyn Crowley, Hansraj R. Bookun, David N. McClure

published 30 Dec 2025

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A screening strategy for bioactive components from Amaranth: An integrated approach of network pharmacology, molecular docking and molecular dynamics simulation

Zixuan Zhao, Zhengxin Huang, Kaiming Wang, Hua Zhang, Ying Ren, Jinjin Tong

published 26 Dec 2025

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Integrated transcriptomic analysis reveals a CEBPB–DUSP1 axis driving tumor progression in colorectal cancer

Huarong Zhou, Lili Fang

published 18 Dec 2025

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Therapeutic mechanism of Pithecellobium clypearia Benth. on imiquimod-induced psoriasis revealed by tissue transcriptomics in mice

Xiyuan He, Yueting Mo, Peixin Shi, Yini Xu, Mingmei Zhou, Ting Zhang

published 12 Dec 2025

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Control of quiescence and activation of human muscle stem cells by cytokines

Katharine Striedinger, Emilie Barruet, Elena Atamaniauc, Karla Linquist, Chris Knott, Andrew Brack, Jason H. Pomerantz

published 05 Dec 2025

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CRE-Ter enhances murine bone differentiation, improves muscle cell atrophy, and increases irisin expression

Sompot Jantarawong, Wipapan Khimmaktong, Pharkphoom Panichayupakaranant, Yutthana Pengjam

published 04 Dec 2025

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