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Macromolecular engineering

Bottom-up synthesis of protein-based nanomaterials from engineered β-solenoid proteins

Zeyu Peng, Maria D. R. Peralta, Daniel L. Cox, Michael D. Toney

Directed Evolution of Aminoglycoside Phosphotransferase (3′) Type IIIa Variants That Inactivate Amikacin but Impose Significant Fitness Costs

Joseph R. Kramer, Ichiro Matsumura

Discovery of potent and specific inhibitors targeting the active site of MMP-9 from the engineered SPINK2 library

Hidenori Yano, Daisuke Nishimiya, [ ... ], Ryuji Hashimoto

Probing the Effector and Suppressive Functions of Human T Cell Subsets Using Antigen-Specific Engineered T Cell Receptors

Qi Wan, Lina Kozhaya, [ ... ], Derya Unutmaz

Genetically Engineered Yeast Expressing a Lytic Peptide from Bee Venom (Melittin) Kills Symbiotic Protozoa in the Gut of Formosan Subterranean Termites

Claudia Husseneder, Jennifer R. Donaldson, Lane D. Foil

Seven N-terminal Residues of a Thermophilic Xylanase Are Sufficient to Confer Hyperthermostability on Its Mesophilic Counterpart

Shan Zhang, Yongzhi He, Haiying Yu, Zhiyang Dong

Next generation calmodulin affinity purification: Clickable calmodulin facilitates improved protein purification

Julia G. Fraseur, Tamara L. Kinzer-Ursem

Engineering of long-acting human growth hormone-Fc fusion proteins: Effects of valency, fusion position, and linker design on pharmacokinetics and efficacy

Taekyeol Lee, Dongsop Lee, [ ... ], Jaehoon Choi

Directed Evolution and Resolution Mechanism of 1, 3-Propanediol Oxidoreductase from Klebsiella pneumoniae toward Higher Activity by Error-Prone PCR and Bioinformatics

Wei Jiang, Yuan Zhuang, Shizhen Wang, Baishan Fang

The scale-free nature of protein sequence space

Patrick C. F. Buchholz, Catharina Zeil, Jürgen Pleiss

Selection of RNAs for Constructing “Lighting-UP” Biomolecular Switches in Response to Specific Small Molecules

Tamaki Endoh, Naoki Sugimoto

An L213A variant of β-glycosidase from Sulfolobus solfataricus with increased α-L-arabinofuranosidase activity converts ginsenoside Rc to compound K

Ji-Hyeon Choi, Kyung-Chul Shin, Deok-Kun Oh

The register shift rules for βαβ-motifs for de novo protein design

Hiroto Murata, Hayao Imakawa, Nobuyasu Koga, George Chikenji

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