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Macromolecular engineering

Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-Fold

John D. Steemson, Matthias Baake, [ ... ], Mark T. Liddament

Improving Glyphosate Oxidation Activity of Glycine Oxidase from Bacillus cereus by Directed Evolution

Tao Zhan, Kai Zhang, [ ... ], Ziduo Liu

Engineering of long-acting human growth hormone-Fc fusion proteins: Effects of valency, fusion position, and linker design on pharmacokinetics and efficacy

Taekyeol Lee, Dongsop Lee, [ ... ], Jaehoon Choi

Mutagenic Organized Recombination Process by Homologous In Vivo Grouping (MORPHING) for Directed Enzyme Evolution

David Gonzalez-Perez, Patricia Molina-Espeja, Eva Garcia-Ruiz, Miguel Alcalde

Conjugation of Proteins by Installing BIO-Orthogonally Reactive Groups at Their N-Termini

Nagasundarapandian Soundrarajan, Sriram Sokalingam, [ ... ], Sun-Gu Lee

Structure of an Engineered β-Lactamase Maltose Binding Protein Fusion Protein: Insights into Heterotropic Allosteric Regulation

Wei Ke, Abigail H. Laurent, [ ... ], Focco van den Akker

Complex Structure of Engineered Modular Domains Defining Molecular Interaction between ICAM-1 and Integrin LFA-1

Sungkwon Kang, Chae Un Kim, [ ... ], Moonsoo M. Jin

A Polypeptide-DNA Hybrid with Selective Linking Capability Applied to Single Molecule Nano-Mechanical Measurements Using Optical Tweezers

Fatemeh Moayed, Alireza Mashaghi, Sander J. Tans

Functional Mutation of Multiple Solvent-Exposed Loops in the Ecballium elaterium Trypsin Inhibitor-II Cystine Knot Miniprotein

Richard H. Kimura, Douglas S. Jones, [ ... ], Jennifer R. Cochran

A Coarse-Grained Approach to Protein Design: Learning from Design to Understand Folding

Ivan Coluzza

Engineering Proteins for Thermostability with iRDP Web Server

Priyabrata Panigrahi, Manas Sule, [ ... ], C. G. Suresh

Protein Trans-Splicing of an Atypical Split Intein Showing Structural Flexibility and Cross-Reactivity

Huiling Song, Qing Meng, Xiang-Qin Liu

Fitness Loss and Library Size Determination in Saturation Mutagenesis

Yuval Nov

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