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Macromolecular engineering

Directed Chemical Evolution with an Outsized Genetic Code

Casey J. Krusemark, Nicolas P. Tilmans, Patrick O. Brown, Pehr B. Harbury

published 10 Aug 2016

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Genetically Engineered Yeast Expressing a Lytic Peptide from Bee Venom (Melittin) Kills Symbiotic Protozoa in the Gut of Formosan Subterranean Termites

Claudia Husseneder, Jennifer R. Donaldson, Lane D. Foil

published 17 Mar 2016

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Three Recombinant Engineered Antibodies against Recombinant Tags with High Affinity and Specificity

Hongyu Zhao, Ao Shen, Yang K. Xiang, David P. Corey

published 04 Mar 2016

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Reformatting Rituximab into Human IgG2 and IgG4 Isotypes Dramatically Improves Apoptosis Induction In Vitro

Jennifer D. Könitzer, Annette Sieron, Angelika Wacker, Barbara Enenkel

published 29 Dec 2015

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Directed Evolution and Resolution Mechanism of 1, 3-Propanediol Oxidoreductase from Klebsiella pneumoniae toward Higher Activity by Error-Prone PCR and Bioinformatics

Wei Jiang, Yuan Zhuang, Shizhen Wang, Baishan Fang

published 03 Nov 2015

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Engineering Proteins for Thermostability with iRDP Web Server

Priyabrata Panigrahi, Manas Sule, Avinash Ghanate, Sureshkumar Ramasamy, C. G. Suresh

published 05 Oct 2015

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A Web Resource for Standardized Benchmark Datasets, Metrics, and Rosetta Protocols for Macromolecular Modeling and Design

Shane Ó Conchúir, Kyle A. Barlow, Roland A. Pache, Noah Ollikainen, Kale Kundert, Matthew J. O'Meara, Colin A. Smith, Tanja Kortemme

published 03 Sep 2015

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Computational Design of the β-Sheet Surface of a Red Fluorescent Protein Allows Control of Protein Oligomerization

Timothy M. Wannier, Matthew M. Moore, Yun Mou, Stephen L. Mayo

published 15 Jun 2015

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In-Frame Amber Stop Codon Replacement Mutagenesis for the Directed Evolution of Proteins Containing Non-Canonical Amino Acids: Identification of Residues Open to Bio-Orthogonal Modification

James A. J. Arpino, Amy J. Baldwin, Adam R. McGarrity, Eric M. Tippmann, D. Dafydd Jones

published 26 May 2015

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Contribution of Disulfide Bridges to the Thermostability of a Type A Feruloyl Esterase from Aspergillus usamii

Xin Yin, Die Hu, Jian-Fang Li, Yao He, Tian-Di Zhu, Min-Chen Wu

published 13 May 2015

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Modeling Analysis of Signal Sensitivity and Specificity by Vibrio fischeri LuxR Variants

Deanna M. Colton, Eric V. Stabb, Stephen J. Hagen

published 11 May 2015

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Towards the Systematic Mapping and Engineering of the Protein Prenylation Machinery in Saccharomyces cerevisiae

Viktor Stein, Marta H. Kubala, Jason Steen, Sean M. Grimmond, Kirill Alexandrov

published 13 Mar 2015

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Desired Alteration of Protein Affinities: Competitive Selection of Protein Variants Using Yeast Signal Transduction Machinery

Misato Kaishima, Nobuo Fukuda, Jun Ishii, Akihiko Kondo

published 22 Sep 2014

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