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Macromolecular engineering

Antibody Engineering Using Phage Display with a Coiled-Coil Heterodimeric Fv Antibody Fragment

Xinwei Wang, Pinyu Zhong, Peter P. Luo, Kevin C. Wang

Directed evolution to improve the catalytic efficiency of urate oxidase from Bacillus subtilis

Wenjie Li, Shouteng Xu, [ ... ], Jiong Hong

Pharmacological characterization of potent and selective Na_V1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

Bryan D. Moyer, Justin K. Murray, [ ... ], Les P. Miranda

Reformatting Rituximab into Human IgG2 and IgG4 Isotypes Dramatically Improves Apoptosis Induction In Vitro

Jennifer D. Könitzer, Annette Sieron, Angelika Wacker, Barbara Enenkel

Mechanism of Protein Kinetic Stabilization by Engineered Disulfide Crosslinks

Inmaculada Sanchez-Romero, Antonio Ariza, [ ... ], Jose M. Sanchez-Ruiz

Computational Design of Binding Proteins to EGFR Domain II

Yoon Sup Choi, Soomin Yoon, [ ... ], Sung Ho Ryu

A Thermostable β-Glucuronidase Obtained by Directed Evolution as a Reporter Gene in Transgenic Plants

Ai-Sheng Xiong, Ri-He Peng, [ ... ], Quan-Hong Yao

Towards the Systematic Mapping and Engineering of the Protein Prenylation Machinery in Saccharomyces cerevisiae

Viktor Stein, Marta H. Kubala, [ ... ], Kirill Alexandrov

In-Frame Amber Stop Codon Replacement Mutagenesis for the Directed Evolution of Proteins Containing Non-Canonical Amino Acids: Identification of Residues Open to Bio-Orthogonal Modification

James A. J. Arpino, Amy J. Baldwin, [ ... ], D. Dafydd Jones

Improving Kinetic or Thermodynamic Stability of an Azoreductase by Directed Evolution

Vânia Brissos, Nádia Gonçalves, Eduardo P. Melo, Lígia O. Martins

The Molecular Basis for the Broad Substrate Specificity of Human Sulfotransferase 1A1

Ilana Berger, Chen Guttman, [ ... ], Amir Aharoni

Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system

Kristin Støen Gunnarsen, Lene Støkken Høydahl, [ ... ], Geir Åge Løset

Three Recombinant Engineered Antibodies against Recombinant Tags with High Affinity and Specificity

Hongyu Zhao, Ao Shen, Yang K. Xiang, David P. Corey

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