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Macromolecular engineering

Designer Self-Assembling Peptide Nanofiber Scaffolds for Adult Mouse Neural Stem Cell 3-Dimensional Cultures

Fabrizio Gelain, Daniele Bottai, Angleo Vescovi, Shuguang Zhang

Identification and Multidimensional Optimization of an Asymmetric Bispecific IgG Antibody Mimicking the Function of Factor VIII Cofactor Activity

Zenjiro Sampei, Tomoyuki Igawa, [ ... ], Kunihiro Hattori

Engineered Monoclonal Antibody with Novel Antigen-Sweeping Activity In Vivo

Tomoyuki Igawa, Atsuhiko Maeda, [ ... ], Kunihiro Hattori

Biological Designer Self-Assembling Peptide Nanofiber Scaffolds Significantly Enhance Osteoblast Proliferation, Differentiation and 3-D Migration

Akihiro Horii, Xiumei Wang, Fabrizio Gelain, Shuguang Zhang

RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design

Po-Ssu Huang, Yih-En Andrew Ban, [ ... ], David Baker

Incorporation of Noncanonical Amino Acids into Rosetta and Use in Computational Protein-Peptide Interface Design

P. Douglas Renfrew, Eun Jung Choi, Richard Bonneau, Brian Kuhlman

Engineering of mCherry variants with long Stokes shift, red-shifted fluorescence, and low cytotoxicity

Yi Shen, Yingche Chen, [ ... ], Robert E. Campbell

New Molecular Reporters for Rapid Protein Folding Assays

Stéphanie Cabantous, Yvonne Rogers, Thomas C. Terwilliger, Geoffrey S. Waldo

The PLOS ONE Synthetic Biology Collection: Six Years and Counting

Jean Peccoud, Mark Isalan

Engineered Protein Nano-Compartments for Targeted Enzyme Localization

Swati Choudhary, Maureen B. Quin, [ ... ], Claudia Schmidt-Dannert

Stabilisation of the Fc Fragment of Human IgG1 by Engineered Intradomain Disulfide Bonds

Gordana Wozniak-Knopp, Johannes Stadlmann, Florian Rüker

Antibody engineering to generate SKY59, a long-acting anti-C5 recycling antibody

Zenjiro Sampei, Kenta Haraya, [ ... ], Junichi Nezu

Targeting G with TAL Effectors: A Comparison of Activities of TALENs Constructed with NN and NK Repeat Variable Di-Residues

Michelle L. Christian, Zachary L. Demorest, [ ... ], Daniel F. Voytas

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