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Lysosomes

Reduced mitochondria membrane potential and lysosomal acidification are associated with decreased oligomeric Aβ degradation induced by hyperglycemia: A study of mixed glia cultures

Yung-Cheng Huang, Shu-Meng Hsu, [ ... ], Huey-Jen Tsay

Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition

Golam T. Saffi, Evan Tang, [ ... ], Roberto J. Botelho

Hydroxynonenal causes Langerhans cell degeneration in the pancreas of Japanese macaque monkeys

Piyakarn Boontem, Tetsumori Yamashima

Cellular and biochemical response to chaperone versus substrate reduction therapies in neuropathic Gaucher disease

Margarita M. Ivanova, Julia Dao, [ ... ], Ozlem Goker-Alpan

Alpha-mannosidosis in Tunisian consanguineous families: Potential involvement of variants in GHR and SLC19A3 genes in the variable expressivity of cognitive impairment

Rahma Mkaouar, Zied Riahi, [ ... ], Mediha Trabelsi

The expression of prosaposin and its receptors, GRP37 and GPR37L1, are increased in the developing dorsal root ganglion

Miho Taniguchi, Hiroaki Nabeka, [ ... ], Seiji Matsuda

The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model

Yixing Wu, Heather T. Whittaker, [ ... ], Frances K. Wiseman

Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model

Nicole K. Polinski, Terina N. Martinez, [ ... ], Kuldip D. Dave

Generation of the short TRIM32 isoform is regulated by Lys 247 acetylation and a PEST sequence

Juncal Garcia-Garcia, Katrine Stange Overå, Waqas Khan, Eva Sjøttem

Genome-wide DNA methylation and RNA-seq analyses identify genes and pathways associated with doxorubicin resistance in a canine diffuse large B-cell lymphoma cell line

Chia-Hsin Hsu, Hirotaka Tomiyasu, Chi-Hsun Liao, Chen-Si Lin

Genetic analysis of the Drosophila ESCRT-III complex protein, VPS24, reveals a novel function in lysosome homeostasis

Jonathan R. Florian, Samuel J. DeMatte, [ ... ], Fumiko Kawasaki

Castration causes an increase in lysosomal size and upregulation of cathepsin D expression in principal cells along with increased secretion of procathepsin D and prosaposin oligomers in adult rat epididymis

Lorena Carvelli, Andrea Carolina Aguilera, [ ... ], Miguel A. Sosa

5-aminolaevulinic acid (5-ALA) accumulates in GIST-T1 cells and photodynamic diagnosis using 5-ALA identifies gastrointestinal stromal tumors (GISTs) in xenograft tumor models

Makiko Sasaki, Mamoru Tanaka, [ ... ], Hiromi Kataoka

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