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Luciferase assay

Deciphering the pathogenicity of three NKX2-1 variants in ultra-severe forms of childhood interstitial lung disease

Yohan David Soreze, Tifenn Desroziers-Louedec, [ ... ], Nadia Nathan

1p-Enh-regulated CYP4B1 alleviates NNK-induced heart failure and lung cancer via the STAT3 pathway

Li Dai, Jun Hu, [ ... ], Xianglin Zuo

LncRNA UCA1 regulates immune micro-environment in cisplatin-induced AKI by miRNA-4498/AKT3 pathway

Peng Hongjun, Lydia Mukanhaire, [ ... ], Ren Xianguo

Novel and effective plasmid transfection protocols for functional analysis of genetic elements in human cardiac fibroblasts

Makoto Matsuyama, Takahiro Iwamiya

The endometrial cancer A230V-ALK5 (TGFBR1) mutant attenuates TGF-β signaling and exhibits reduced in vitro sensitivity to ALK5 inhibitors

Eun-Jeong Yu, Daphne W. Bell

A suboptimal OCT4-SOX2 binding site facilitates the naïve-state specific function of a Klf4 enhancer

Jack B. Waite, RuthMabel Boytz, [ ... ], Sharon E. Torigoe

Valproic acid use is associated with diminished risk of contracting COVID-19, and diminished disease severity: Epidemiologic and in vitro analysis reveal mechanistic insights

Amanda Watson, Pankil Shah, [ ... ], Ronald Rodriguez

Design and evaluation of antisense sequence length for modified mouse U7 small nuclear RNA to induce efficient pre-messenger RNA splicing modulation in vitro

Takenori Shimo, Otoya Ueda, Satoshi Yamamoto

Circ_0000006 and circ_0000160 regulate hsa-let-7e-5p/UBQLN4 axis in aortic dissection progression

Yong Liu, Liang Wang, [ ... ], Yinglong Lai

Side-by-side comparison of published small molecule inhibitors against thapsigargin-induced store-operated Ca²⁺ entry in HEK293 cells

Katherine Norman, Karen E. Hemmings, [ ... ], Marc A. Bailey

The RNA-binding KH-domain in the unique transcription factor of the malaria parasite is responsible for its transcriptional regulatory activity

Kanako Komaki-Yasuda, Shigeyuki Kano

Sensing chemical-induced genotoxicity and oxidative stress via yeast-based reporter assays using NanoLuc luciferase

Minami Shichinohe, Shun Ohkawa, Yuu Hirose, Toshihiko Eki

LucFlow: A method to measure Luciferase reporter expression in single cells

Sunil Nooti, Madison Naylor, [ ... ], Manu

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