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Liver

Multi-omics analysis identifies PPARα as a key inhibitor of hepatocyte ferroptosis in sepsis-associated liver injury

Shi-Ling He, Jian-Chuan Lin, Gao-Fang Wu, He-fan He

published 19 Feb 2026

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Effect of transplanted oligodendrocyte precursor cells derived from inflammatory and non-inflammatory microenvironment on remyelination in a chronic cuprizone model

Hoda Akbari, Iraj Ragerdi-Kashani, Farzaneh Rezaei-Yazdi, Parichehr Pasbakhsh

published 18 Feb 2026

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GATA4-targeted compounds induce apoptosis and diminish viability of hepatoblastoma cells

Sini M. Kinnunen, Katja Eloranta, Marjut Pihlajoki, Mika J. Välimäki, Saana Pohjavaara, Emilie Indersie, Stefano Cairo, Aarni Kuusinen, Heikki Ruskoaho, Markku Heikinheimo

published 11 Feb 2026

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Taurocholic acid induces intrahepatic cholangiocyte cell proliferation via activating NRAS and YAP1

Lum Fube, Arul Thason, Elizabeth Taliaferro, Carol Heckman, Surya Amarachintha

published 04 Feb 2026

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Assessment of antidiabetic, hepatoprotective, and analgesic effects of quinazolinone derivative, (E)-1-Benzoyl-3-((4- (Dimethylamino) Benzylidene) Amino)-2-(4-(Dimethylamino) Phenyl)-2,3 dihydroquinazoline-4(1h)-one, in diabetes induced mice model

Haider Ali, Asif Jan, Gowhar Ali, Syed Shaukat Ali, Abdur Rahim, Ursula Abu Nahla

published 04 Feb 2026

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Sucrose but not arsenic induce hepatic steatosis which correlates with calpain-1 inhibition

Myrian Velasco, Rosa Isela Ortiz-Huidobro, Ana María Salazar, Marcia Hiriart, Patricia Ostrosky-Wegman, Pablo Pánico

published 30 Dec 2025

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Diet-induced steatohepatitis does not cause heart failure with preserved ejection fraction in male middle-aged C57BL/6N mice

Chase W. Kessinger, Lin Chen, Felicia Huang, Jierui Lin, Amanda Davenport, Zhiqiang Lin

published 29 Dec 2025

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Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity

Chizuka Obara, Yohei Iizaka, Akari Mine, Yojiro Anzai, Masako Tada, Shinpei Yamaguchi

published 29 Dec 2025

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Dynamic growth risk of incidentally detected gallbladder polyps–A retrospective, single-center analysis

Sophia Heinrich, Piet Janko ten Thoren, Patrick Behrendt, Jakob Hagenah, Heiner Wedemeyer, Andrej Potthoff, Benjamin Maasoumy

published 23 Dec 2025

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Evaluation of the insulin-dependent and -independent hypoglycemic effects and understanding their breakdown in the progression of obesity using mice

Fusako Kojima, So Morishita, Shinsuke Uda, Noriko Yutsudo, Yoshihiro Ogawa, Hiroyuki Kubota

published 23 Dec 2025

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Autophagy regulates MK-2206-induced LDL receptor expression and cholesterol efflux pathways

Hilde Sundvold, Thea Bismo Strøm

published 04 Dec 2025

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Evaluation of the new blood-pool CT contrast agent VivoVist in mouse models

Eric W. Livingston, Jonathan E. Frank, Spencer V. Thompson, Gregory K. Wilkerson, Jean-Felix Presler, Hong Yuan

published 31 Oct 2025

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Rapid 3D phenotyping of chick embryo liver development at HH22-HH41 embryonic stages using X-ray microcomputed tomography with PTA staining

Igor Rzhepakovsky, Sergei Piskov, Svetlana Avanesyan, Marina Sizonenko, Lyudmila Timchenko, Magomed Shakhbanov, Gloria Nassali, Idrisa Kiryowa, Andrey Nagdalian

published 27 Oct 2025

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