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Hepatocytes

Assessment of antidiabetic, hepatoprotective, and analgesic effects of quinazolinone derivative, (E)-1-Benzoyl-3-((4- (Dimethylamino) Benzylidene) Amino)-2-(4-(Dimethylamino) Phenyl)-2,3 dihydroquinazoline-4(1h)-one, in diabetes induced mice model

Haider Ali, Asif Jan, [ ... ], Ursula Abu Nahla

Sucrose but not arsenic induce hepatic steatosis which correlates with calpain-1 inhibition

Myrian Velasco, Rosa Isela Ortiz-Huidobro, [ ... ], Pablo Pánico

Diet-induced steatohepatitis does not cause heart failure with preserved ejection fraction in male middle-aged C57BL/6N mice

Chase W. Kessinger, Lin Chen, [ ... ], Zhiqiang Lin

Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity

Chizuka Obara, Yohei Iizaka, [ ... ], Shinpei Yamaguchi

Autophagy regulates MK-2206-induced LDL receptor expression and cholesterol efflux pathways

Hilde Sundvold, Thea Bismo Strøm

Humanized monoacylglycerol acyltransferase 2 mice on a high-fat diet exhibit impaired liver detoxification during metabolic dysfunction-associated steatotic liver disease

J. Jose Corbalan, Pranavi Jagadeesan, Joseph T. Nickels Jr

Frizzled 7 drives amplification of cancer stem-cell subpopulations and the aggressiveness and poor differentiation of human hepatocellular carcinoma

Anaïs Lopez, Alexia Paturel, [ ... ], Claude Caron de Fromentel

Gardenia jasminoides fruit extract ameliorates non-alcoholic steatohepatitis with fibrosis by modulating inflammatory and fibrogenic pathways

Natnicha Suttawong, Namthip Witayavanitkul, [ ... ], Duangporn Werawatganon

A new investigation of nonalcoholic fatty liver disease: Effects of hypoxia on mitochondrial function and lipid droplet autophagy

Meiyuan Tian, Yaogang Zhang, [ ... ], Yanyan Ma

Deciphering the role of the lncRNA TRIBAL in hepatocyte models

Sébastien Soubeyrand, Paulina Lau, Ruth McPherson

Hyperuricemia in ob/ob mice relates to hepatocellular pyruvate metabolism/ xanthine oxidase axis

Shan Zhang, Shasha Hu, Haibo Tan, Ertao Jia

Whole genome DNA methylation patterns in tissue and cfDNA associated with fibrosis reflect the complex signature of MASLD

Jongseong Ahn, Soyeon Kim, [ ... ], Jung Weon Lee

Dual effects of indoxyl sulfate on modulation of human hepatic CYP3A activity, with individual differences

Masao Togao, Naoyuki Asakawa, [ ... ], Koji Kawakami

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