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Inflammasomes

A new mechanism regulating microglial NLRP3 inflammasome: FMR1 mediates NLRP3 mRNA stability

Qian Deng, Qianqian Bai, [ ... ], Hua Fan

Multi-omics analysis reveals STING activation mediates NLRP3-related pyroptosis and exacerbates myocardial ischemia-reperfusion injury

Xuehu Zhang, Aoqin Gu, [ ... ], Shaobin Jia

The KEAP1/NRF2 axis controls LPS-induced oxidative stress, inflammasome activation and caspase-1 activity in human endothelial cells

Alba Montero-Jodra, Maria Jesús Estebán-Amo, [ ... ], María Simarro

Impact of Metformin therapy on miR-9, miR-223, and miR-132 and inflammasome-related gen expression in obese and non-obes PCOS patients: A comparative study with healthy controls

Seyed Alireza Mirjalili, Seyed Mehdi Kalantar, [ ... ], Korosh Ashrafi Dehkordi

Evogliptin prevents ceramide-induced pyroptosis during calcification via modulation of NLRP3/GSDM-D mediated pathway in Vascular Smooth Muscle Cells

Razia Rashid Rahil, Salman Shamas, [ ... ], Owais Mohmad Bhat

The role and mechanism of irisin/NLRP3 signal in aerobic exercise ameliorating blood glucose homeostasis in pre-diabetic mice

Shujuan Hu, Zhengkang Wu, [ ... ], Xianwang Wang

NLRP3 inflammasome-dependent and -independent interleukin-1β release by macrophages exposed to wear and corrosion products from CoCrMo implants

Nasteho Abdoulkader, Jennifer Archibald, [ ... ], Isabelle Catelas

β-sitosterol alleviated HFD-induced atherosclerosis by regulating the MAPK/Nrf2/NLRP3 pathway in ApoE^−/− mice

Weiping Wu, Wugao Liu, [ ... ], Jing Jin

CLIC1 down-regulates Nrf2/HO-1 signalling pathway promoting the apoptosis and pyroptosis in OGD/R-treated HT22 cells

Jingtong Xiong, Shuo Li, [ ... ], Chuang Sun

LBH589 reduces oxidized mitochondrial DNA and suppresses NLRP3 inflammasome activation to relieve pulmonary inflammation

Changwen Ning, Fenghua Gao, [ ... ], Qun Yu

Role of rosuvastatin and pitavastatin in alleviating diabetic cardiomyopathy in rats: Targeting of RISK, NF-κB/ NLRP3 inflammasome and TLR4/ NF-κB signaling cascades

Dalia O. Saleh, Nesma M.E. Abo El Nasr, [ ... ], Ingy M. Hashad

Placental inflammation is increased in gestational diabetes mellitus: The role of inflammasome NLRP-3 and chemokine scavenger decoy receptor D6

Marianna Onori, Giuliana Beneduce, [ ... ], Chiara Tersigni

Kaempferol inhibits oxidative stress and reduces macrophage pyroptosis by activating the NRF2 signaling pathway

Yu Wang, Chaofan Chen, [ ... ], Chuanyu Gao

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