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Genomics

Comprehensive profiling of circRNAs reveals stimulus-specific networks and core regulators of cellular senescence

Mingxia Ge, Zimo Liu, Xiaoxiao Zhao, Xiaodong Zhan, Shan Jiang

published 27 Feb 2026

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Dapagliflozin mitigates myocardial inflammation and metabolic stress in heart failure through STAT1 inhibition: Evidence from multi-omics analyses and experimental exploration

Lianqi He, Di Zhang, Shiwen Zhang, Zhichao Ren, Yihong Huangfu, Xiran Cheng, Zhanchun Song

published 27 Feb 2026

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Analysis of the correlation between vaginal microbiota and high-risk human papillomavirus infection and cervical lesions

Yan Chen, Wei Qiu, Guolong Xiao, Rujing Zhang, Linlin Zhang

published 27 Feb 2026

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Distinct mutational landscapes and phylogenomic insights of the SARS-CoV-2 delta variant in Pakistan and India: Regional evolution, novel mutations, and epidemiological implications

Nazia Fiaz, Atia Basheer, Imran Zahoor, Saima Naveed, Tahir Yaqub

published 27 Feb 2026

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Temporal dynamics and functional annotation of transcriptome rhythmicity in HEK293T cells

Yuling Sun, Huiyu Dong, Fei Ge, Ying Zhao, Shuhan Yang, Yidong Ding, Min Dong, Liming Wang, Tao Zhang

published 26 Feb 2026

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Beyond the transcript: Chromatin implications in trans-splicing in Trypanosomatids

Romina Trinidad Zambrano Siri, Paula Beati, Lucas Inchausti, Pablo Smircich, Guillermo Daniel Alonso, Josefina Ocampo

published 26 Feb 2026

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Exploring structural, functional, evolutionary, and genetic characteristics of sugar transporters in maize and their roles in abiotic stress tolerance

Md. Sohel Mia, Md Suzauddula, Tao Yang, Rui Li, Fang Li, Jianbo Mi, Chao Xia, Tanveer A. Wani, Seema Zargar, M. Atikur Rahman, Md. Mahmudul Hasan

published 26 Feb 2026

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Assessing the biopotency of the rAAV9 vector In Vitro

Pratikshya Adhikari, Peter G. Nichols, Stephen M. Vorobiov, Tierra A. Bobo, Haiyan Fu

published 26 Feb 2026

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Based on single-cell and transcriptome analysis of inflammatory pathway biomarkers and their molecular mechanisms in chronic obstructive pulmonary disease

Yaping Zhou, Hui Gong, Zelin Hao, Lu Wang, Li Li, Xiaoguang Zou

published 25 Feb 2026

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Unexpected diversification of DENV2 genotype III in Colombia: New Insights and application of the globalized nomenclature

Eliana P. Calvo, Leidy Johana Madroñero, Lenny Marcela Hernández, Jhann Andrés Arturo, Hernando Pinzón, Félix Giovanni Delgado, Myriam Lucia Velandia-Romero, Verity Hill, Nathan D. Grubaugh, Jaime Eduardo Castellanos

published 24 Feb 2026

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Comprehensive analysis of the potential effect and mechanism of pyroptosis-related genes in treatment-related myeloid tumors

Jing Cheng, Weiyue Fang, Hongxia Tan, Xiaoxia Zhan, Xiaohui Zhu

published 24 Feb 2026

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Transcriptomic suppression of immune and ECM stability in skeletal muscle of patients with chronic kidney disease

Luke A. Baker, Nicholas Eastley, Robert U. Ashford, Matthew Denniff, Matthew Graham-Brown, Emma L. Watson

published 24 Feb 2026

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Understanding the gut microbiome through a fitness intervention of aerobic and resistance training for individuals with type 2 diabetes mellitus (GUTFIT: A Study Protocol)

Amy M. Thomson, Dominique C. Drost, Neil M. Johannsen, Cristoforo Silvestri, Martin Sénéchal

published 23 Feb 2026

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