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Genome complexity

DeepDRA: Drug repurposing using multi-omics data integration with autoencoders

Taha Mohammadzadeh-Vardin, Amin Ghareyazi, Ali Gharizadeh, Karim Abbasi, Hamid R. Rabiee

published 26 Jul 2024

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A framework for block-wise missing data in multi-omics

Sergi Baena-Miret, Ferran Reverter, Esteban Vegas

published 23 Jul 2024

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Design and evaluation of antisense sequence length for modified mouse U7 small nuclear RNA to induce efficient pre-messenger RNA splicing modulation in vitro

Takenori Shimo, Otoya Ueda, Satoshi Yamamoto

published 09 Jul 2024

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Copy number variant detection using next-generation sequencing in EYS-associated retinitis pigmentosa

Masakazu Hiraoka, Yusaku Urakawa, Kanako Kawai, Akiko Yoshida, Junichi Hosakawa, Masaki Takazawa, Akira Inaba, Satoshi Yokota, Yasuhiko Hirami, Masayo Takahashi, Osamu Ohara, Yasuo Kurimoto, Akiko Maeda

published 24 Jun 2024

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Nematode histone H2A variant evolution reveals diverse histories of retention and loss and evidence for conserved core-like variant histone genes

Swadha Singh, Noelle Anderson, Diana Chu, Scott W. Roy

published 30 May 2024

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Copy number variant scan in more than four thousand Holstein cows bred in Lombardy, Italy

Andrea Delledonne, Chiara Punturiero, Carlotta Ferrari, Francesca Bernini, Raffaella Milanesi, Alessandro Bagnato, Maria G. Strillacci

published 21 May 2024

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Leishmania Ribosomal Protein (RP) paralogous genes compensate each other’s expression maintaining protein native levels

Francisca S. Borges, José C. Quilles Jr, Lucas B. Lorenzon, Caroline R. Espada, Felipe Freitas-Castro, Tânia P. A. Defina, Fabíola B. Holetz, Angela K. Cruz

published 16 May 2024

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Genome-wide analysis of MADS-box transcription factor gene family in wild emmer wheat (Triticum turgidum subsp. dicoccoides)

Ghader Mirzaghaderi

published 07 Mar 2024

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De novo copy number variations in candidate genomic regions in patients of severe autism spectrum disorder in Vietnam

Hoa Thi Phuong Bui, Duong Huy Do, Ha Thi Thanh Ly, Kien Trung Tran, Huong Thi Thanh Le, Kien Trung Nguyen, Linh Thi Dieu Pham, Hau Duc Le, Vinh Sy Le, Arijit Mukhopadhyay, Liem Thanh Nguyen

published 07 Mar 2024

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Identification of MYC intron 2 regions that modulate expression

Van S. Tompkins, Zheng Xue, Jake M. Peterson, Warren B. Rouse, Collin A. O’Leary, Walter N. Moss

published 18 Jan 2024

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Role of the redox state of the Pirin-bound cofactor on interaction with the master regulators of inflammation and other pathways

Tamim Ahsan, Sabrina Samad Shoily, Tasnim Ahmed, Abu Ashfaqur Sajib

published 30 Nov 2023

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Molecular characterization of G6PD mutations identifies new mutations and a high frequency of intronic variants in Thai females

Kamonwan Chamchoy, Sirapapha Sudsumrit, Jutamas Wongwigkan, Songsak Petmitr, Duantida Songdej, Emily R. Adams, Thomas Edwards, Ubolsree Leartsakulpanich, Usa Boonyuen

published 15 Nov 2023

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Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice

Thomas J. Sproule, Robert Y. Wilpan, Benjamin E. Low, Kathleen A. Silva, Deepak Reyon, J. Keith Joung, Michael V. Wiles, Derry C. Roopenian, John P. Sundberg

published 05 Oct 2023

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