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Genetically modified organisms

Effects of KCNQ2 Gene Truncation on M-Type Kv7 Potassium Currents

Jon Robbins, Gayle M. Passmore, Fe C. Abogadie, Joanne M. Reilly, David A. Brown

published 20 Aug 2013

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Establishment of Mouse Model of MYH9 Disorders: Heterozygous R702C Mutation Provokes Macrothrombocytopenia with Leukocyte Inclusion Bodies, Renal Glomerulosclerosis and Hearing Disability

Nobuaki Suzuki, Shinji Kunishima, Makoto Ikejiri, Shoichi Maruyama, Michihiko Sone, Akira Takagi, Masahito Ikawa, Masaru Okabe, Tetsuhito Kojima, Hidehiko Saito, Tomoki Naoe, Tadashi Matsushita

published 20 Aug 2013

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Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy

Clara Theunis, Natalia Crespo-Biel, Valérie Gafner, Maria Pihlgren, María Pilar López-Deber, Pedro Reis, David T. Hickman, Oskar Adolfsson, Nathalie Chuard, Dorin Mlaki Ndao, Peter Borghgraef, Herman Devijver, Fred Van Leuven, Andrea Pfeifer, Andreas Muhs

published 19 Aug 2013

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Epigenetic Changes of Lentiviral Transgenes in Porcine Stem Cells Derived from Embryonic Origin

Kwang-Hwan Choi, Jin-Kyu Park, Hye-Sun Kim, Kyung-Jun Uh, Dong-Chan Son, Chang-Kyu Lee

published 19 Aug 2013

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A Role for NF-κB Activity in Skin Hyperplasia and the Development of Keratoacanthomata in Mice

Brian Poligone, Matthew S. Hayden, Luojing Chen, Alice P. Pentland, Eijiro Jimi, Sankar Ghosh

published 19 Aug 2013

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FRAP Analysis Reveals Stabilization of Adhesion Structures in the Epidermis Compared to Cultured Keratinocytes

Henry P. Foote, Kaelyn D. Sumigray, Terry Lechler

published 19 Aug 2013

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Rapid Cohort Generation and Analysis of Disease Spectrum of Large Animal Model of Cone Dystrophy

Corinne Kostic, Simon Geoffrey Lillico, Sylvain Vincent Crippa, Nicolas Grandchamp, Héloïse Pilet, Stéphanie Philippe, Zen Lu, Tim James King, Jacques Mallet, Chamsy Sarkis, Yvan Arsenijevic, Christopher Bruce Alexander Whitelaw

published 19 Aug 2013

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Ablation of RIC8A Function in Mouse Neurons Leads to a Severe Neuromuscular Phenotype and Postnatal Death

Katrin Ruisu, Keiu Kask, Riho Meier, Merly Saare, Raivo Raid, Alar Veraksitš, Alar Karis, Tambet Tõnissoo, Margus Pooga

published 16 Aug 2013

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ApoER2 and VLDLr Are Required for Mediating Reelin Signalling Pathway for Normal Migration and Positioning of Mesencephalic Dopaminergic Neurons

Ahmed Sharaf, Hans H. Bock, Björn Spittau, Elisabeth Bouché, Kerstin Krieglstein

published 16 Aug 2013

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Octyl Gallate Markedly Promotes Anti-Amyloidogenic Processing of APP through Estrogen Receptor-Mediated ADAM10 Activation

She-Qing Zhang, Darrell Sawmiller, Song Li, Kavon Rezai-Zadeh, Huayan Hou, Shufeng Zhou, Douglas Shytle, Brian Giunta, Frank Fernandez, Takashi Mori, Jun Tan

published 15 Aug 2013

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CD36 and Fyn Kinase Mediate Malaria-Induced Lung Endothelial Barrier Dysfunction in Mice Infected with Plasmodium berghei

Ifeanyi U. Anidi, Laura E. Servinsky, Otgonchimeg Rentsendorj, R. Scott Stephens, Alan L. Scott, David B. Pearse

published 15 Aug 2013

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Loss of the Nuclear Receptor Corepressor SLIRP Compromises Male Fertility

Shane M. Colley, Larissa Wintle, Richelle Searles, Victoria Russell, Renee C. Firman, Stephanie Smith, Kathleen DeBoer, D. Jo Merriner, Ben Genevieve, Jacqueline M. Bentel, Bronwyn G. A. Stuckey, Michael R. Phillips, Leigh W. Simmons, David M. de Kretser, Moira K. O'Bryan, Peter J. Leedman

published 15 Aug 2013

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Intracellular Reprogramming of Expression, Glycosylation, and Function of a Plant-Derived Antiviral Therapeutic Monoclonal Antibody

Jeong-Hwan Lee, Da-Young Park, Kyung-Jin Lee, Young-Kwan Kim, Yang-Kang So, Jae-Sung Ryu, Seung-Han Oh, Yeon-Soo Han, Kinarm Ko, Young-Kug Choo, Sung-Joo Park, Robert Brodzik, Kyoung-Ki Lee, Doo-Byoung Oh, Kyung-A Hwang, Hilary Koprowski, Yong Seong Lee, Kisung Ko

published 15 Aug 2013

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