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Genetically modified animals

Development of transgenic models susceptible and resistant to SARS-CoV-2 infection in FVB background mice

Sun-Min Seo, Jae Hyung Son, [ ... ], Yang-Kyu Choi

A cardiac-null mutation of Prdm16 causes hypotension in mice with cardiac hypertrophy via increased nitric oxide synthase 1

Ji-One Kang, Tae Woong Ha, [ ... ], Bermseok Oh

Deletion of SM22α disrupts the structure and function of caveolae and T-tubules in cardiomyocytes, contributing to heart failure

Jun Wu, Wei Wang, [ ... ], Mei Han

Sex-, age-, and organ-dependent improvement of bile acid hydrophobicity by ursodeoxycholic acid treatment: A study using a mouse model with human-like bile acid composition

Hajime Ueda, Akira Honda, [ ... ], Tadashi Ikegami

Mitochondrial dysfunction is associated with lipid metabolism disorder and upregulation of angiotensin-converting enzyme 2

Qian Zhao, Xiaoshan Zhou, [ ... ], Anna Karlsson

Metabolic changes in vitamin D receptor knockout mice

Sue Lynn Lau, Rebecca A. Stokes, [ ... ], Jenny E. Gunton

Pattern of tamoxifen-induced Tie2 deletion in endothelial cells in mature blood vessels using endo SCL-Cre-ERT transgenic mice

Peter J. Zwiers, Rianne M. Jongman, [ ... ], Grietje Molema

Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles

Andrew R. Castle, Serene Wohlgemuth, Luis Arce, David Westaway

Resveratrol-nitric oxide donor hybrid effect on priapism in sickle cell and nitric oxide-deficient mouse

Andressa Kely Pinheiro, Dalila Andrade Pereira, [ ... ], Fábio Henrique Silva

15-PGDH regulates hematopoietic and gastrointestinal fitness during aging

Won Jin Ho, Julianne N. P. Smith, [ ... ], Amar B. Desai

Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome

Claudia Cannavo, Karen Cleverley, [ ... ], Frances K. Wiseman

Holocarboxylase synthetase knockout is embryonic lethal in mice

Mahrou Sadri, Haichuan Wang, [ ... ], Janos Zempleni

The voltage-gated Ca²⁺ channel subunit α₂δ-4 regulates locomotor behavior and sensorimotor gating in mice

Annette Klomp, Ryotaro Omichi, [ ... ], Amy Lee

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