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Genetic engineering

Overexpression of TCP9-like gene enhances salt tolerance in transgenic soybean

Zhuo Zhang, Yuanling Zhao, Yifan Chen, Yueming Li, Lijun Pan, Siyu Wang, Piwu Wang, Sujie Fan

published 26 Jul 2023

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Seven naturally variant loci serve as genetic modifiers of Lamc2^jeb induced non-Herlitz junctional Epidermolysis Bullosa in mice

Thomas J. Sproule, Vivek M. Philip, Nabig A. Chaudhry, Derry C. Roopenian, John P. Sundberg

published 12 Jul 2023

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Optimization of piggyBac transposon-mediated gene transfer method in common marmoset embryos

Nanami Kohri, Mitsuo Ota, Hikaru Kousaku, Eiko N. Minakawa, Kazuhiko Seki, Ikuo Tomioka

published 09 Jun 2023

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Targeted deletion of grape retrotransposon associated with fruit skin color via CRISPR/Cas9 in Vitis labrascana ‘Shine Muscat’

Ikuko Nakajima, Hiroyuki Kawahigashi, Chikako Nishitani, Akifumi Azuma, Takashi Haji, Seiichi Toki, Masaki Endo

published 08 Jun 2023

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Effects of T cell leptin signaling on systemic glucose tolerance and T cell responses in obesity

Kaitlin Kiernan, Amanda G. Nichols, Yazan Alwarawrah, Nancie J. MacIver

published 05 Jun 2023

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Binding of Tau-derived peptide-fused GFP to plant microtubules in Arabidopsis thaliana

Hiroshi Inaba, Kazusato Oikawa, Kazuya Ishikawa, Yutaka Kodama, Kazunori Matsuura, Keiji Numata

published 02 Jun 2023

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Mice lacking Ptprd exhibit deficits in goal-directed behavior and female-specific impairments in sensorimotor gating

Emily V. Ho, Amanda Welch, Summer L. Thompson, James A. Knowles, Stephanie C. Dulawa

published 19 May 2023

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A novel soybean hairy root system for gene functional validation

Bruna Medeiros Pereira, Fabrício Arraes, Andressa Cunha Quintana Martins, Nayara Sabrina Freitas Alves, Bruno Paes Melo, Carolina Vianna Morgante, Mario Alfredo Passos Saraiva, Maria Fátima Grossi-de-Sá, Patricia Messenberg Guimaraes, Ana Cristina Miranda Brasileiro

published 18 May 2023

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Genetically modified crops do not present variations in pollen viability and morphology when compared to their conventional counterparts

Daniel Soares, Hallison Vertuan, Fabiana Bacalhau, Marcia José, Augusto Crivellari, Gustavo G. Belchior, Geraldo U. Berger

published 01 May 2023

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A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates

Danish M. Anwer, Francesco Gubinelli, Yunus A. Kurt, Livija Sarauskyte, Febe Jacobs, Chiara Venuti, Ivette M. Sandoval, Yiyi Yang, Jennifer Stancati, Martina Mazzocchi, Edoardo Brandi, Gerard O’Keeffe, Kathy Steece-Collier, Jia-Yi Li, Tomas Deierborg, Fredric P. Manfredsson, Marcus Davidsson, Andreas Heuer

published 01 May 2023

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Synonymous alterations of cancer-associated Trp53 CpG mutational hotspots cause fatal developmental jaw malocclusions but no tumors in knock-in mice

Richard J. Epstein, Frank P. Y. Lin, Robert A. Brink, James Blackburn

published 13 Apr 2023

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Bioengineering of a Lactococcus lactis subsp. lactis strain enhances nisin production and bioactivity

Roxana Portieles, Hongli Xu, Feng Chen, Jingyao Gao, Lihua Du, Xiangyou Gao, Carlos Borroto Nordelo, Qiulin Yue, Lin Zhao, Nayanci Portal Gonzalez, Ramon Santos Bermudez, Orlando Borrás-Hidalgo

published 10 Apr 2023

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Preclinical trials in Alzheimer’s disease: Sample size and effect size for behavioural and neuropathological outcomes in 5xFAD mice

Mahvish Faisal, Jana Aid, Bekzod Nodirov, Benjamin Lee, Miriam A. Hickey

published 10 Apr 2023

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