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Genetic engineering

A novel soybean hairy root system for gene functional validation

Bruna Medeiros Pereira, Fabrício Arraes, [ ... ], Ana Cristina Miranda Brasileiro

Genetically modified crops do not present variations in pollen viability and morphology when compared to their conventional counterparts

Daniel Soares, Hallison Vertuan, [ ... ], Geraldo U. Berger

A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates

Danish M. Anwer, Francesco Gubinelli, [ ... ], Andreas Heuer

Synonymous alterations of cancer-associated Trp53 CpG mutational hotspots cause fatal developmental jaw malocclusions but no tumors in knock-in mice

Richard J. Epstein, Frank P. Y. Lin, Robert A. Brink, James Blackburn

Bioengineering of a Lactococcus lactis subsp. lactis strain enhances nisin production and bioactivity

Roxana Portieles, Hongli Xu, [ ... ], Orlando Borrás-Hidalgo

Preclinical trials in Alzheimer’s disease: Sample size and effect size for behavioural and neuropathological outcomes in 5xFAD mice

Mahvish Faisal, Jana Aid, [ ... ], Miriam A. Hickey

In vitro spermatogenesis in isolated seminiferous tubules of immature mice

Xuemin Feng, Takafumi Matsumura, [ ... ], Takehiko Ogawa

A seeding-based neuronal model of tau aggregation for use in drug discovery

Ines S. Amorim, Sylvie Challal, [ ... ], Patricia Machado

High signal-to-noise imaging of spontaneous and 5 ns electric pulse-evoked Ca²⁺ signals in GCaMP6f-expressing adrenal chromaffin cells isolated from transgenic mice

Ciara Viola, Thomas W. Gould, [ ... ], Gale L. Craviso

Precision engineering of biological function with large-scale measurements and machine learning

Drew S. Tack, Peter D. Tonner, [ ... ], David Ross

Mitotic CDK1 and 4E-BP1 II: A single phosphomimetic mutation in 4E-BP1 induces glucose intolerance in mice

Simon Cao, Michael J. Jurczak, [ ... ], Patrick S. Moore

Targeting nonsense-mediated RNA decay does not increase progranulin levels in the Grn ^R493X mouse model of frontotemporal dementia

Denise M. Smith, Michael L. Niehoff, [ ... ], Andrew D. Nguyen

An optimized electrotransformation protocol for Lactobacillus jensenii

Elsa Fristot, Thomas Bessede, [ ... ], Guillaume Cambray

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