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Gene expression

Genome-wide identification and multi-dimensional functional characterization of the SIR2 family in Brassica napus L.

Hanbing Hu, Ling He, Rui Chen, Ziheng Jing, Heping Wan, Zilan Xiao, Hongtao Cheng, Chunhong Wu, Xiaoyun Liu

published 22 Jan 2026

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The shared biomarkers and molecular mechanisms of systemic lupus erythematosus and type 2 diabetes

Dawei Yang, Youqi Zhang, Liu Ji, Jianjun Wu, Fan Yang

published 22 Jan 2026

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Nicotinamide mononucleotide improves spermatogenesis in aluminium-exposed mice by inhibiting NLRP3-mediated pyroptosis

Weihua Nong, Qiumei Huang, Sheng Dou, Yanhong Wei, Yanlun Song, Junli Wang, Xiaocan Lei, Fenglian Yang, Liqiao He

published 22 Jan 2026

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Integrative multi-omics analyses identify key genes and elucidate bidirectional regulatory mechanisms in thyroid dysfunction

Yilang Hu, Hong Hu, Lijun Xu, Xuzheng Tang, Chongyu Wang, Zhengyi Lian, Chenyu Xie, Zhiwan Xie, Qingqing Wang

published 22 Jan 2026

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RIPK2 induces docetaxel resistance in prostate cancer through the NF-κB/P-gp signaling pathway

Shaoqiang Xing, Zhaoliang Xu, Sheng Zeng, Minghao Yue, Wenzhou Xing, Qian Liu

published 21 Jan 2026

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Multi-omics analysis and functional validation of CHEK1 as an independent prognostic biomarker in Pancreatic cancer

Xiaonan Wei, Ruirong Yan, Shanshan Wang, Yaru Jiang, Haibin Li, Yanping Li

published 21 Jan 2026

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Immortalization and characterization of Schwann cell lines derived from NF1-associated cutaneous neurofibromas

Hua Li, Alexander Pemov, Robert Allaway, David F. Muir, Lung-Ji Chang, Jineta Banerjee, Alexandra J. Scott, Jaime M.W. Nagy, Jian Liu, Meritxell Carrió, Helena Mazuelas, Anthony Yachnis, Sang Y. Lee, Xiaochun Zhang, Yang Lyu, Douglas R. Stewart, Angela Hirbe, Jaishri O. Blakeley, Eduard Serra, Deeann Wallis, Margaret R. Wallace

published 21 Jan 2026

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Elucidate senescence-related gene signature and immune infiltration landscape in abdominal aortic aneurysm

Jingde Li, Ru Ying, Jing Luo, Xin Guo, Min Zhang

published 20 Jan 2026

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Secretory leukocyte protease inhibitor (SLPI) promotes cholangiocarcinoma progression via inflammation-associated and vasculogenic mechanisms

Kangsadan Chueajedton, Chaiwat Chueaiphuk, Jeranan Inpad, Sarawut Kumphune, Worasak Kaewkong, Damratsamon Surangkul, Kanlayanee Sawanyawisuth, Ubon Cha’on, Suchada Phimsen

published 20 Jan 2026

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Prediction of myeloid malignant cells in Fanconi anemia using machine learning

Luis A. Flores-Mejía, Pablo Siliceo, Ulises Juárez Figueroa, Angel A. De la Cruz, Cecilia Ayala-Zambrano, Hugo Tovar, Sara Frías, Alfredo Rodríguez

published 20 Jan 2026

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Cell death-related gene signatures as dual-function biomarkers: Early diagnosis and therapeutic targeting in Staphylococcus aureus pneumonia

Cao Qing, Wanjuan Sun, Chaomian Yang, Yien Yao, Qiong Liang, Tianxia Huang, Lu Lin

published 20 Jan 2026

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Dynamical modeling of TNF-α, IL-6, and IL-10 interactions in stroke-induced inflammation

Fozia Ali M. Arishi, Azmin Sham Rambely, Fatimah Abdul Razak

published 20 Jan 2026

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Oxyphenbutazone improves memory and learning impairments in LPS-induced neurotoxicity via modulating TGF-β/NF-κB/IκB-α pathways: In silico and in vivo study

Khalid Saad Alharbi, Muhammad Afzal, Sattam Khulaif Alenezi, Reem ALQahtani, Tariq G. Alsahli, Faisal Imam, Imran Kazmi

published 20 Jan 2026

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