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Gene expression

Microarray-based analysis reveals a novel role of the miRNA-613/SNAI2/CXCR4 axis in atrial fibrillation

Zhenyu Zhai, Yiligong Qi, Longlong Hu, Zumao Gan

published 23 Jun 2025

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Genomic profiling in hidradenitis suppurativa: InterOmics pipeline for DNA-RNA sequencing highlights HLA variants, keratin-associated mutations and extracellular matrix alterations as contributing factors to HS pathogenesis

Lucas André Cavalcanti Brandão, Ronald Rodrigues de Moura, Bruno Rodrigo Assunção, Cecilia Del Vecchio, Adamo Pio d’Adamo, Gudrun Ratzinger, Barbara Böckle, Nina Frischhut, Wolfram Jaschke, Matthias Schmuth, Muhammad Suleman, Angelo Valerio Marzano, Chiara Moltrasio, Paola Maura Tricarico, Sergio Crovella

published 20 Jun 2025

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NOMO-1 cells expressing an NF-κB luciferase reporter gene facilitate a simple, rapid monocyte activation test that can detect a wide range of pyrogens

Tomohisa Nanao, Yuki Marutani, Katsuko Sato, Tomohiro Mori, Takeshi Kitagawa, Teruaki Oku, Takahiro Nishibu

published 20 Jun 2025

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Time matters: Transcriptomic insights into temporally regulated reproductive and physiological processes in the life cycle of salps

Svenja J. Müller, Ilenia Urso, Sara Driscoll, Katharina Michael, Gabriele Sales, Cristiano de Pittà, Wiebke Wessels, Bettina Meyer

published 20 Jun 2025

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In Silico molecular docking and molecular dynamic simulation of transferrin coated Phenytoin loaded SLNs with molecular targets of epilepsy

Ahmad Zeb, Hussain Ali, Jehan Zeb Khan, Fawad Ali Shah, Abdullah Alattar, Fawaz E. Alanazi

published 20 Jun 2025

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Uncovering common disease mechanisms and critical biomarkers in Crohn’s disease with concurrent psoriasis and exploring potential therapeutic agents

Tianqi Liu, Xiaoqing Zhang, Ruiqi Chen, Yifan Sun, Ruijian Zhang, Liwen Zhang, Zhepeng Luo, Jiani Wang

published 20 Jun 2025

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Short tandem repeat variants are possibly associated with RNA secondary structure and gene expression

Nick Kinney, Dikshya Pathak, Emma Evans, Paola Arias

published 18 Jun 2025

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AKR1C2 silencing promotes ferroptosis and inhibits proliferation, migration, and invasion in lung cancer cells

Yi Cui, Zhihui Liu

published 18 Jun 2025

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Editing metacaspase (StMC7) gene enhances late blight resistance in Russet Burbank potato

Bikram Poudel, Atul Sathe, Jacqueline C. Bede, Ajjamada C. Kushalappa

published 18 Jun 2025

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Dynamic CYP2E1 expression and metabolic activity changes in male rats during immune liver injury and sex differences in alcohol metabolism

Jiayi Zhang, Yingying Cao, Ziqi Jin, Runa A, Xiaoxue Wang, Lingyu Zhang, Yingqi Hu, Yongzhi Xue

published 18 Jun 2025

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Effect of retinoic acid treatment on the retinoic acid signaling pathway in a human siRNA-based aniridia limbal epithelial cell model, in vitro

Shao-Lun Hsu, Tanja Stachon, Fabian N. Fries, Zhen Li, Shuailin Li, Shanhe Liu, Berthold Seitz, Swarnali Kundu, Maryam Amini, Shweta Suiwal, Nóra Szentmáry

published 18 Jun 2025

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Aging dimensions and markers as relative predictors of mortality in a longitudinal epidemiological sample

Kristian E. Markon, Frank D. Mann, Colin D. Freilich, Steve Cole, Robert F. Krueger

published 18 Jun 2025

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Circulating exosome-circRNAs mediated downregulation of FGF9 through ceRNA mechanism aggravates renal fibrosis in diabetic nephropathy

Donglin Yang, Rongjiang Yin, Xiaomin Zhang, Xiaohui Wang, Xiaobin Pei, Zijie Guo, Pengyue Qiao, Kehan Zhu, Lin Wang, Pengchao Du

published 17 Jun 2025

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