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Fluorescence polarization

Direct activation of HSF1 by macromolecular crowding and misfolded proteins

Oliver Simoncik, Vlastimil Tichy, Michal Durech, Lenka Hernychova, Filip Trcka, Lukas Uhrik, Miroslav Bardelcik, Philip J. Coates, Borivoj Vojtesek, Petr Muller

published 04 Nov 2024

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Polarization and cell-fate decision facilitated by the adaptor Ste50p in Saccharomyces cerevisiae

Nusrat Sharmeen, Chris Law, Cunle Wu

published 20 Dec 2022

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Design and synthesis of Nrf2-derived hydrocarbon stapled peptides for the disruption of protein-DNA-interactions

Bianca Wiedemann, Dominic Kamps, Laura Depta, Jörn Weisner, Jana Cvetreznik, Stefano Tomassi, Sascha Gentz, Jan-Erik Hoffmann, Matthias P. Müller, Oliver Koch, Leif Dehmelt, Daniel Rauh

published 22 Jun 2022

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Aurintricarboxylic acid is a canonical disruptor of the TAZ-TEAD transcriptional complex

Kepeng Che, Ajaybabu V. Pobbati, Caleb N. Seavey, Yuriy Fedorov, Anton A. Komar, Ashley Burtscher, Shuang Ma, Brian P. Rubin

published 13 Apr 2022

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Sex-specific and concentration-dependent influence of Cremophor RH 40 on ampicillin absorption via its effect on intestinal membrane transporters in rats

Heyue Yin, Haibin Shao, Jing Liu, Yujia Qin, Wenbin Deng

published 28 Feb 2022

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A positive feedback loop involving the Spa2 SHD domain contributes to focal polarization

Michael J. Lawson, Brian Drawert, Linda Petzold, Tau-Mu Yi

published 08 Feb 2022

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A comparative study on the use of microscopy in pharmacology and cell biology research

Agatha M. Reigoto, Sarah A. Andrade, Marianna C. R. R. Seixas, Manoel L. Costa, Claudia Mermelstein

published 22 Jan 2021

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Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1

Guillaume Gaullier, Genevieve Roberts, Uma M. Muthurajan, Samuel Bowerman, Johannes Rudolph, Jyothi Mahadevan, Asmita Jha, Purushka S. Rae, Karolin Luger

published 03 Nov 2020

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Grifolin, neogrifolin and confluentin from the terricolous polypore Albatrellus flettii suppress KRAS expression in human colon cancer cells

Almas Yaqoob, Wai Ming Li, Victor Liu, Chuyi Wang, Sebastian Mackedenski, Linda E. Tackaberry, Hugues B. Massicotte, Keith N. Egger, Kerry Reimer, Chow H. Lee

published 05 May 2020

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m⁶A minimally impacts the structure, dynamics, and Rev ARM binding properties of HIV-1 RRE stem IIB

Chia-Chieh Chu, Bei Liu, Raphael Plangger, Christoph Kreutz, Hashim M. Al-Hashimi

published 11 Dec 2019

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Highly sensitive biomolecular interaction detection method using optical bound/free separation with grating-coupled surface plasmon field-enhanced fluorescence spectroscopy (GC-SPFS)

Takatoshi Kaya, Satoru Nagatoishi, Kosuke Nagae, Yukito Nakamura, Kohei Tsumoto

published 01 Aug 2019

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Substituted anthraquinones represent a potential scaffold for DNA methyltransferase 1-specific inhibitors

Rebecca L. Switzer, Jessica Medrano, David A. Reedel, Jill Weiss

published 15 Jul 2019

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The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release

Maria Pia Negroni, Lawrence J. Stern

published 02 Jul 2018

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