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Esters

Highly Functionalized 1,2–Diamino Compounds through Reductive Amination of Amino Acid-Derived β–Keto Esters

Paula Pérez-Faginas, M. Teresa Aranda, M. Teresa García-López, Lourdes Infantes, Asia Fernández-Carvajal, José Manuel González-Ros, Antonio Ferrer-Montiel, Rosario González-Muñiz

published 07 Jan 2013

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PKC Activation by Resveratrol Derivatives with Unsaturated Aliphatic Chain

Satyabrata Pany, Anjoy Majhi, Joydip Das

published 21 Dec 2012

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Differential Requirement for Protein Synthesis in Presynaptic Unmuting and Muting in Hippocampal Glutamate Terminals

Devon C. Crawford, Xiaoping Jiang, Amanda Taylor, Krista L. Moulder, Steven Mennerick

published 13 Dec 2012

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Targeting Fatty Acid Binding Protein (FABP) Anandamide Transporters – A Novel Strategy for Development of Anti-Inflammatory and Anti-Nociceptive Drugs

William T. Berger, Brian P. Ralph, Martin Kaczocha, Jing Sun, Trent E. Balius, Robert C. Rizzo, Samir Haj-Dahmane, Iwao Ojima, Dale G. Deutsch

published 07 Dec 2012

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Polymorphs and Prodrugs and Salts (Oh My!): An Empirical Analysis of “Secondary” Pharmaceutical Patents

Amy Kapczynski, Chan Park, Bhaven Sampat

published 05 Dec 2012

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Glucose Metabolic Trapping in Mouse Arteries: Nonradioactive Assay of Atherosclerotic Plaque Inflammation Applicable to Drug Discovery

Richard G. Conway, Eyassu Chernet, David C. De Rosa, Robert J. Benschop, Anne B. Need, Emily C. Collins, James S. Bean, J. Michael Kalbfleisch, Mark D. Rekhter

published 28 Nov 2012

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Remarkable Diversity in the Enzymes Catalyzing the Last Step in Synthesis of the Pimelate Moiety of Biotin

Madelyn M. Shapiro, Vandana Chakravartty, John E. Cronan

published 09 Nov 2012

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Structures of SHV-1 β-Lactamase with Penem and Penam Sulfone Inhibitors That Form Cyclic Intermediates Stabilized by Carbonyl Conjugation

Wei Ke, Priyaranjan Pattanaik, Christopher R. Bethel, Anjaneyulu Sheri, John D. Buynak, Robert A. Bonomo, Focco van den Akker

published 08 Nov 2012

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O:2-CRM₁₉₇ Conjugates against Salmonella Paratyphi A

Francesca Micoli, Simona Rondini, Massimiliano Gavini, Luisa Lanzilao, Donata Medaglini, Allan Saul, Laura B. Martin

published 07 Nov 2012

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The Metagenome-Derived Enzymes LipS and LipT Increase the Diversity of Known Lipases

Jennifer Chow, Filip Kovacic, Yuliya Dall Antonia, Ulrich Krauss, Francesco Fersini, Christel Schmeisser, Benjamin Lauinger, Patrick Bongen, Joerg Pietruszka, Marlen Schmidt, Ina Menyes, Uwe T. Bornscheuer, Marrit Eckstein, Oliver Thum, Andreas Liese, Jochen Mueller-Dieckmann, Karl-Erich Jaeger, Wolfgang R. Streit

published 24 Oct 2012

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A Spiroligomer α-Helix Mimic That Binds HDM2, Penetrates Human Cells and Stabilizes HDM2 in Cell Culture

Zachary Z. Brown, Kavitha Akula, Alla Arzumanyan, Jennifer Alleva, Marcus Jackson, Eugeney Bichenkov, Joel B. Sheffield, Mark A. Feitelson, Christian E. Schafmeister

published 18 Oct 2012

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ExpI and PhzI Are Descendants of the Long Lost Cognate Signal Synthase for SdiA

Anice Sabag-Daigle, Brian M. M. Ahmer

published 17 Oct 2012

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Oroxylin-A Rescues LPS-Induced Acute Lung Injury via Regulation of NF-κB Signaling Pathway in Rodents

Tzu-Ling Tseng, Mei-Fang Chen, Ming-Jen Tsai, Yung-Hsiang Hsu, Chin-Piao Chen, Tony J. F. Lee

published 10 Oct 2012

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