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Enzymology

A chemically optimized, GalNAc-conjugated siRNA targeting HSD17B13 demonstrates efficacy in a human 3D organoid model of MASH, showcasing an alternative to animal testing

Qin Meng, Xujia Wang, Yuxuan Zhang, Sudeep Pushpakom, Jun Yang, Hui Feng, Mu Wang

published 14 Aug 2026

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Histochemical alteration, protein nitration, and antioxidant expression in oysters as early warning indicators for microplastic contamination in the Texas Gulf Coast

Rebecca Muñiz, Md Faisal Amin, Md Saydur Rahman

published 12 Aug 2026

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Diagnostic agreement between Rhinoswabs and joint nose and throat swabs for the detection of influenza and SARS-CoV-2 among symptomatic ambulatory patients in Hong Kong

Caitriona Murphy, Samuel M. S. Cheng, Loretta Mak, Hau Chi So, Dennis K. M. Ip, Malik Peiris, Benjamin J. Cowling

published 11 Aug 2026

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Exogenous application of α-Ionone and Methyl jasmonate induces metabolite-based response in Alstroemeria and reduces feeding damage by Western Flower Thrips

Andrés F. Velasco-Cárdenas, Daniel Rodríguez, Ericsson Coy-Barrera

published 11 Aug 2026

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Effects of neem extract on Artemia franciscana: Insights from high-throughput transcriptomics and phenotypic analysis

Rodolfo Farlora, Paulina Bustos, Eugene M. Tine, Eduardo Jeria, Alex Eapen, Padmakumar Pillai, Jorge Pino, Donald I. Brown, Kathleen Whitlock

published 11 Aug 2026

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Influence of pelleting and β-mannanase on nutrient digestibility and metabolizable energy of DDGS, copra meal, palm kernel meal, and jatropha meal in precision-fed Single Comb White Leghorn roosters

Bounmy Keohavong, Musabbir Ahammed, Jong Suh Shin, Lohakare Jayant, Sang Jip Ohh

published 07 Aug 2026

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Tyro3 facilitates cytoplasmic delivery of extracellular vesicle contents and antigen presentation via major histocompatibility complex class I in dendritic cells

Takashi Koyama, Katsuhiko Kojima, Koki Maeda, Takahide Matsui, Hitomi Kosai, Noriko Ishida, Eiji Morita, Mitsunori Fukuda, Nobuyuki Tanaka

published 04 Aug 2026

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Morphological characteristics and optimized protocols for in vitro germination and viability testing of Idesia polycarpa Maxim. Pollen

Zhoujun Zhu, Bin Xu, Junru Zhao, Li Wang, Yeye Zhang, Ran Yang, Rui Wang, Jugang Wang, Jianxin Li, Chao Gao

published 03 Aug 2026

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Concordant RNA-protein evidence and human tissue metabolomics prioritize UPP1-associated nucleotide remodeling in prostate cancer

Xuancai Chen, Wei Su, Qun Zhou, Yucheng Qi, Juanjuan Xie, Yachun Tang, Xin Tang, Hao Fu

published 31 Jul 2026

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Crystal structure of a closed ternary complex of a HNA Reverse Transcriptase in complex with a HNA/DNA duplex

Cédric Gutfreund, Mikhail Abramov, Frédérick Coosemans, Philipp Holliger, Piet Herdewijn, Karin Betz, Andreas Marx

published 31 Jul 2026

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Bioassay-guided isolation of antioxidant, antibacterial, and antidiabetic compounds from Aleuritopteris bicolor of Nepal: In vitro/in silico study

Rekha Bhandari, Sadikshya Sapkota, Peru Kumari Bishwakarma, Shailendra Kumar Sharma, Ram Kishor Yadav, Sandesh Poudel, Siddha Raj Upadhyaya, Ganga Ram Upadhayay, Sajan L. Shyaula, Khem Raj Joshi

published 30 Jul 2026

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Mechanistic evaluation of NSC 57774 as a SHP2 inhibitor in gastric cancer: Multi-pathway signaling modulation in vitro

Ghalia Khoder, Rose Ghemrawi, Nour Sammani, Rania Harati, Mohamad Hamad, Jibran Sualeh Muhammad, Walaa Mousa, Mostafa Khair

published 30 Jul 2026

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De Ritis (AST/ALT) ratio as a predictor of early adverse outcomes following transcatheter aortic valve replacement

Haitham Abu Khadija, Jebrin Alkrinawi, Ali Abdullah, Omar Ayyad, Ammar Barakat, Salma Najjar, Alexander Kogan, Leonid Sternik, Alaa Shehady, Mohammad Masu’d, Duha Najajra, Mohammad Alnees

published 28 Jul 2026

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