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Enzymology

In vitro 5-LOX inhibitory and antioxidant potential of isoxazole derivatives

Waqas Alam, Haroon Khan, [ ... ], Ahmed A. Elhenawy

Heavy water inhibits DNA double-strand break repairs and disturbs cellular transcription, presumably via quantum-level mechanisms of kinetic isotope effects on hydrolytic enzyme reactions

Takeshi Yasuda, Nakako Nakajima, [ ... ], Katsushi Tajima

A suboptimal OCT4-SOX2 binding site facilitates the naïve-state specific function of a Klf4 enhancer

Jack B. Waite, RuthMabel Boytz, [ ... ], Sharon E. Torigoe

Cytotoxicity of bendamustine, alone and in combination with novel agents, toward adult T-cell leukemia cells

Naoki Osada, Jiro Kikuchi, [ ... ], Yusuke Furukawa

Modelling the effects of 4-factor prothrombin complex concentrate for the management of factor Xa-associated bleeding

Ineke Muir, Eva Herzog, [ ... ], Maureane Hoffman

Signal-sensing triggers the shutdown of HemKR, regulating heme and iron metabolism in the spirochete Leptospira biflexa

Juan Andrés Imelio, Felipe Trajtenberg, [ ... ], Alejandro Buschiazzo

A novel viral RNA detection method based on the combined use of trans-acting ribozymes and HCR-FRET analyses

Leonardo Ferreira da Silva, Aisel Valle Garay, [ ... ], Cíntia Marques Coelho

Aβ_25-35-induced autophagy and apoptosis are prevented by the CRMP2-derived peptide ST2-104 (R9-CBD3) via a CaMKKβ/AMPK/mTOR signaling hub

Yingshi Ji, Jinghong Ren, [ ... ], Li Sun

Feasibility of Vis-NIR spectroscopy approach to predict soil biological attributes in arid land soils

Elias Hosseini, Mehdi Zarei, [ ... ], Hasan Mozaffari

Alpha-fetoprotein and des-gamma-carboxy prothrombin can predict the objective response of patients with hepatocellular carcinoma receiving durvalumab plus tremelimumab therapy

Issei Saeki, Shigeo Shimose, [ ... ], Hepatology InVestigator Experts in Japan (HIVE-J) Study Group

Biostimulators with marine algae extracts and their role in increasing tolerance to drought stress in highbush blueberry cultivation

Agnieszka Lenart, Dariusz Wrona, Tomasz Krupa

Cu(II)-tyrosinase enzyme catalyst mediated synthesis of mosquito larvicidal active pyrazolidine-3,5-dione derivatives with molecular docking studies and their ichthyotoxicity analysis

Velmurugan Loganathan, SurendraKumar Radhakrishnan, [ ... ], Akbar Idhayadhulla

Laccase-mediated chemoselective C-4 arylation of 5-aminopyrazoles

Mansour Shahedi, Rojina Shahani, [ ... ], Mehdi Mohammadi

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