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Enzymology

A chemically optimized, GalNAc-conjugated siRNA targeting HSD17B13 demonstrates efficacy in a human 3D organoid model of MASH, showcasing an alternative to animal testing

Qin Meng, Xujia Wang, [ ... ], Mu Wang

Histochemical alteration, protein nitration, and antioxidant expression in oysters as early warning indicators for microplastic contamination in the Texas Gulf Coast

Rebecca Muñiz, Md Faisal Amin, Md Saydur Rahman

Diagnostic agreement between Rhinoswabs and joint nose and throat swabs for the detection of influenza and SARS-CoV-2 among symptomatic ambulatory patients in Hong Kong

Caitriona Murphy, Samuel M. S. Cheng, [ ... ], Benjamin J. Cowling

Exogenous application of α-Ionone and Methyl jasmonate induces metabolite-based response in Alstroemeria and reduces feeding damage by Western Flower Thrips

Andrés F. Velasco-Cárdenas, Daniel Rodríguez, Ericsson Coy-Barrera

Effects of neem extract on Artemia franciscana: Insights from high-throughput transcriptomics and phenotypic analysis

Rodolfo Farlora, Paulina Bustos, [ ... ], Kathleen Whitlock

Influence of pelleting and β-mannanase on nutrient digestibility and metabolizable energy of DDGS, copra meal, palm kernel meal, and jatropha meal in precision-fed Single Comb White Leghorn roosters

Bounmy Keohavong, Musabbir Ahammed, [ ... ], Sang Jip Ohh

Tyro3 facilitates cytoplasmic delivery of extracellular vesicle contents and antigen presentation via major histocompatibility complex class I in dendritic cells

Takashi Koyama, Katsuhiko Kojima, [ ... ], Nobuyuki Tanaka

Morphological characteristics and optimized protocols for in vitro germination and viability testing of Idesia polycarpa Maxim. Pollen

Zhoujun Zhu, Bin Xu, [ ... ], Chao Gao

Concordant RNA-protein evidence and human tissue metabolomics prioritize UPP1-associated nucleotide remodeling in prostate cancer

Xuancai Chen, Wei Su, [ ... ], Hao Fu

Crystal structure of a closed ternary complex of a HNA Reverse Transcriptase in complex with a HNA/DNA duplex

Cédric Gutfreund, Mikhail Abramov, [ ... ], Andreas Marx

Bioassay-guided isolation of antioxidant, antibacterial, and antidiabetic compounds from Aleuritopteris bicolor of Nepal: In vitro/in silico study

Rekha Bhandari, Sadikshya Sapkota, [ ... ], Khem Raj Joshi

Mechanistic evaluation of NSC 57774 as a SHP2 inhibitor in gastric cancer: Multi-pathway signaling modulation in vitro

Ghalia Khoder, Rose Ghemrawi, [ ... ], Mostafa Khair

De Ritis (AST/ALT) ratio as a predictor of early adverse outcomes following transcatheter aortic valve replacement

Haitham Abu Khadija, Jebrin Alkrinawi, [ ... ], Mohammad Alnees

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