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Enzyme chemistry

Expanding the toolkit of LacI/GalR chimeras

Carter J. Gray, Pierce T. O’Neil, Kristen M. Schwingen, Carrie Hillebrand, Liskin Swint-Kruse

published 07 Apr 2026

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Effects of increasing molybdenum under low nitrogen input on yield, nitrogen-metabolizing enzymes and nitrogen use efficiency of winter wheat cultivars

Di Yang, Qixia Wu, Youning Wang

published 05 Mar 2026

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Regulatory mechanisms of amino acid metabolic pathways in Rhododendron chrysanthum Pall. Under UV-B stress

Jie Lyu, Xiangqun Li, Wang Yu, Xiangru Zhou, Hongwei Xu, Xiaofu Zhou

published 02 Mar 2026

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Prevalence of polypharmacy and drug interactions in geriatric patients: A cross-sectional study from India

Umaima Farheen Khaiser, Rokeya Sultana, Ranajit Das, Saeed G. Alzahrani, Madhumitha Kannan, Mohammed Khairt Newigy, Mohammed Sharique Ahmed Quadri, Mujeeb Ahmed Shaikh, Farha M. Shaikh, Mohammad Fareed

published 11 Feb 2026

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Biodegradation of polyethylene terephthalate microplastics by Paenibacillus naphthalenovorans PETKKU2: Response surface optimization and genomic evidence for an alternative degradation mechanism

Aophat Choonut, Nantharat Wongfaed, Auraiwan Poolpol, Sophon Boonlue, Kitirote Wantala, Onruthai Pinyakong, Pensri Plangklang, Alissara Reungsang

published 04 Feb 2026

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Phytophthora capsici carries and differentially expresses genes for the RNA interference pathway

Jacobo Sevillano-Serrano, Fernando Uriel Rojas-Rojas, Alfonso Méndez-Bravo, Nancy Calderón-Cortés, Harumi Shimada-Beltrán, Julio Vega-Arreguín

published 30 Jan 2026

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Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity

Chizuka Obara, Yohei Iizaka, Akari Mine, Yojiro Anzai, Masako Tada, Shinpei Yamaguchi

published 29 Dec 2025

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Structural flexibility of the nicotinamide group of NADH in butanol dehydrogenase YqdH from Fusobacterium nucleatum

Xue Bai, Ki Hyun Nam, Yongbin Xu

published 17 Dec 2025

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Lysine p-nitroanilide impairs cellular energetics and potentiates statin-induced cytotoxicity in RD rhabdomyosarcoma cells

Johan Alvarado-Calderón, Guillermo Juárez-Vega, Jesús Rosendo Martínez-Arellano, Hilda Sánchez-Vidal, Imelda Cecilia Zarzoza-Mendoza, David Morales-Morales, Juan Manuel Germán-Acacio, Rogelio Rodríguez-Sotres, Lilia G. Noriega, José Carlos Páez-Franco

published 04 Dec 2025

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Renal and hepatic function is preserved following inducible knockout of kynurenine pathway enzymes KMO or QPRT in adult mice

Benjamin S. Summers, Luke Milham, Sonia Bustamante, Krishan Gondal, Peggy Rentsch, Gayathri Sundaram, Michael D. Lovelace, Bryce Vissel, Bruce J. Brew

published 04 Dec 2025

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Translocation of benzo(a)pyrene reactive metabolites across human mammary epithelial cell membranes

B. Alex Merrick, Ashley M. Brooks, Julie F. Foley, Betty K. Mansfield, James K. Selkirk

published 03 Dec 2025

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Glucose priming effect on microbial intercellular metabolic flux diversity in a marine intertidal sediment

Tao Ji, Zhiao Xu, Lihong Wen, Yuxue Yang, Yue Wu, Xueqin Zhao, Ruilian Yao, Rulong Liu, Yunping Xu, Weichao Wu

published 26 Nov 2025

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Optimizing blood alcohol concentration measurement with breath alcohol meter and its preliminary application in evaluating CYP2E1 activity

Jiayi Zhang, Yingqi Hu, Ziqi Jin, Runa A, Xiaoxue Wang, Lingyu Zhang, Yongzhi Xue

published 31 Oct 2025

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