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Drug research and development

Short report: Targeted analysis of whole exome sequencing data in Indian cryptogenic stroke patients

Priya Dev, Jenefer M. Blackwell, Rajiv Kumar, Vijay Mishra, Abhishek Pathak

published 20 Feb 2026

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DrugReasoner: Interpretable drug approval prediction with a reasoning-augmented language model

Mohammadreza Ghaffarzadeh-Esfahani, Ali Motahharynia, Nahid Yousefian, Navid Mazrouei, Jafar Ghaisari, Yousof Gheisari

published 19 Feb 2026

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Effect of virtual group counseling based on health literacy on the empowerment and self-care of pregnant women: A randomized controlled trial

Zahra Rezaee, Fatemeh Bakouei, Hajar Adib-Rad, Soraya Khafri, Zeinab Gholamnia Shirvani, Farzaneh Khorsand

published 19 Feb 2026

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Longevity of different in-office treatments for dentin hypersensitivity: A 6-month randomized and parallel clinical trial

Fernanda de Souza e Silva Ramos, André Luiz Fraga Briso, Érika Mayumi Omoto, Edgar Dutra Zanotto, Paulo Henrique dos Santos, Bruna Perazza, Ticiane Cestari Fagundes

published 17 Feb 2026

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Use as directed? A comparison of software tools intended to check rigor and transparency of published work

Peter Eckmann, Adrian Barnett, Alexandra Bannach-Brown, Elisa Pilar Bascunan Atria, Guillaume Cabanac, Louise Delwen Owen Franzen, Małgorzata Anna Gazda, Kaitlyn Hair, James Howison, Halil Kilicoglu, Cyril Labbe, Sarah McCann, Vladislav Nachev, Martijn Roelandse, Maia Salholz-Hillel, Robert Schulz, Gerben ter Riet, Colby Vorland, Anita Bandrowski, Tracey Weissgerber

published 13 Feb 2026

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Assessing allocation bias in stratified clinical trials with multi-component endpoints evaluated using the stratified Wei-Lachin test

Stefanie Schoenen, Nicole Heussen, Ralf-Dieter Hilgers

published 13 Feb 2026

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Analysis and mining of adverse events associated with vorapaxar: A FAERS database-based study

Hui Zhang, Minghao Lin, Chaoqun Song, Zheng Nan, Dexi Zhao, Yujuan Fu

published 13 Feb 2026

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Evaluation of the effectiveness of a multimodal aspiration prevention system in stroke rehabilitation nursing

Xibo Sun, Xiulan Wu, Yamei Zhang, Ming Lu, ChongRui Feng, ChuRong Liu, YouMing Gu, FaHua Lu, LiRong Liu, GengBiao Zhang, Zulin Dou, Zhanhao Liu

published 12 Feb 2026

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EC2Seq2Sql: Patient-trial matching with LLM agents

Liu Yang, Yongzhong Han, Liang Liu, Xiaoyan Jiang, Ying Li, Jihan Huang, Qianmin Su

published 12 Feb 2026

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Effect of targeted temperature management on neurological and survival outcomes in patients undergoing extracorporeal cardiopulmonary resuscitation

Chi Chan Lee, Yu-Yu Tu, Ping-Yi Lin, You-Cian Lin

published 10 Feb 2026

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Safety population size and duration of exposure prior to approval of new medicines: A database analysis of medicines centralised approved in the European Union between 2011 and 2023

Luísa Bouwman, Hubert Leufkens, Bruno Sepodes, Carla Torre

published 09 Feb 2026

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Beyond the counter: Pharmacists’ preparedness and response strategies in terrorism-related emergencies in Quetta, Pakistan

Fahad Saleem, Fazal ur Rehman Khilji, Sajjad Haider, Qaiser Iqbal, Baharudin Ibrahim, Fatiha Hana Shabaruddin, Mohammad Bashaar

published 06 Feb 2026

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Efficacy and safety of Galgeun-tang-ga-cheongung-sinyi for nasal congestion with common cold: A study protocol for randomized, double-blind, placebo-controlled, parallel, multicenter clinical trial

Seong-Cheon Woo, Yee Ran Lyu, Byong-Kab Kang, Bok-Nam Seo, Ae-Ran Kim, Boram Lee, Yang Chun Park

published 05 Feb 2026

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