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Drug research and development

Variability among large language models in assessing CONSORT compliance of published randomized clinical trials

Daniel Y. Tsybulnik, Justin J. Gillette, Thomas F. Heston

published 22 Sep 2026

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Effects on deep dry needling of the TIBIALIS posterior muscle on plantar pressure distribution: A single-blinded randomized controlled baropodometric trial

María Carmen Martínez-González, Sonia del-Río-Medina, Sergio Montero-Navarro, Jesús Sánchez-Más, María-Isabel Rocha-Ortiz, Francisco-Javier Molina-Payá, Cristina Orts-Ruiz, Cristina Salar-Andreu, Luis-Eduardo Calderón-Santos, José-Martín Botella-Rico, Jaume Morera-Balaguer

published 22 Sep 2026

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Implementing the MATILDA intervention to enhance community participation for older adults with intellectual disability: A feasibility randomised controlled trial and RE-AIM guided process evaluation

Laurence Taggart, Allison Campbell, Isobel Doherty, Kim Ensue, Haleemah Ahmed, Andrew Hanna, Lindsay Armstrong, Jiazhou Ding, Brendan Bunting, Assympta Ryan, Ciaran O’Neil, Mike Clarke, Brendan Leahy, Susie Willis, Janet Schofield, Roger Stancliffe, Angela Hassiotis

published 22 Sep 2026

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“A better system” – managing the adverse effects of prescribed medicines: Cluster-randomised controlled trial and process evaluation of the ADRe Profile in primary care

Vera Logan, Alex Conboy, Neil Carter, David Hughes, Adam Turner, Alan Watkins, Sue Jordan

published 18 Sep 2026

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An adapted enhanced social prescribing intervention vs. usual care in the treatment of loneliness in cancer survivors: Study protocol for a feasibility pilot randomized controlled trial

Brooke Ike, Allison Cole, Brennan Keiser, Alison Tu, Madison Holcroft, Sebastian Tong

published 18 Sep 2026

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Deterministic and stochastic interventions in reducing drug–drug interactions in inappropriate prescribing: A systematic review

Muhammad Fahmi Ahmad Zuber, Nur Aishah Che Roos, Ruzanna Mat Jusoh, Nurulhuda A Manaf

published 17 Sep 2026

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Safety profile of entrectinib in NSCLC: Multi-source pharmacovigilance analysis using FAERS and JADER

JiaLe Yang, JiaWen Liu, GuanBo Zhao, HeChen Li, Ge Sun

published 15 Sep 2026

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Herbal or conventional medicine? A cross-sectional study of Jordanian university students’ preferences for cold and flu treatment

Mohammad Al-magableh, Abdulrhman H.M. Muhaisen, Rama M. Ateir, Shatha A. Abu_Eraq, Hanan O. Hamed, Sama M. Al Atoum, Reem Bani Amer, Soha S. AlShirah

published 15 Sep 2026

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Representation of drug addiction in Pakistani print media: A Latent Dirichlet Allocation analysis

Saad Zahid, Muhammad Nawaz, Kanwal Zahra

published 15 Sep 2026

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Assessing the accuracy and efficiency of an electronic platform for managing childhood illnesses in rural China: A cluster randomized controlled trial

Puhong Zhang, Yang Zhao, Jie Shang, Duolikun Nadila, Tao Li, Yu Liu, Gulizat Abdurixit, Jane Elizabeth Hirst

published 15 Sep 2026

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Sino-US-DrugQA: A benchmark for evaluating large language models in cross-jurisdictional pharmaceutical regulation

Xuejing Fu, Zhen Chen, Wentao Lu

published 15 Sep 2026

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Levofloxacin-associated tendon disorders: Sex-, age-, and route-specific disproportionality analysis using FAERS and JADER

Toshihisa Nakashima, Yoshihiro Noguchi, Rikuto Masuda, Tomoaki Yoshimura

published 11 Sep 2026

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Functional electrical stimulation for major depressive disorder: Protocol for a pilot randomized controlled trial

Fatemeh Gholamali Nezhad, Haochen Yu, Ilya Demchenko, Stephanie N. Iwasa, Stephanie DiNunzio, Rayna Ghosh, José Zariffa, Kei Masani, Wendy Lou, Benoit H. Mulsant, Hani E. Naguib, Milos R. Popovic, Venkat Bhat

published 10 Sep 2026

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