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DNA modification

Genome-wide DNA methylation and transcriptome sequencing analyses of lens tissue in an age-related mouse cataract model

Yuzhu Hu, Dongmei Su, Yue Zhang, Yanjiang Fu, Sijia Li, Xiaoya Chen, Xiao Zhang, Shunfei Zheng, Xu Ma, Shanshan Hu

published 30 Jan 2025

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Comprehensive analysis of ceRNA Networks in UCEC: Prognostic and therapeutic implications

Li Fan, Mengqiu Lan, Xiaohua Wei, Lili Wei, Liuhong Yang, Liuying Nong, Jiajia Wei, Jingjing Li, Wenjie Huang

published 30 Jan 2025

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The type of diet consumed during prepuberty modulates plasma cholesterol, hepatic LXRα expression, and DNA methylation and hydroxymethylation during adulthood in male rats

Ana Aguilar-Lozano, Berenice Palacios-González, Martha Guevara-Cruz, Armando R. Tovar, Alam Palma-Guzman, Lilia G. Noriega

published 24 Jan 2025

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Hypomethylation of IL6ST promotes development of endometriosis by activating JAK2/STAT3 signaling pathway

Yue Hu, Hailong Chen, Lijuan Jin, Xiumei Chi, Jian Zhao, Qinying Cao

published 16 Jan 2025

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Methylome profiling of cell-free DNA during the early life course in (un)complicated pregnancies using MeD-seq: Protocol for a cohort study embedded in the prospective Rotterdam periconception cohort

Marjolein M. van Vliet, Sam Schoenmakers, Ruben G. Boers, Lotte E. van der Meeren, Joost Gribnau, Régine P. M. Steegers-Theunissen

published 09 Jan 2025

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Hypermethylation at 45S rDNA promoter in cancers

Trang Thi Quynh Tran, Trang Hien Do, Tung The Pham, Phương Thi Thu Luu, Oanh Minh Pham, Uyen Quynh Nguyen, Linh Dieu Vuong, Quang Ngoc Nguyen, Tuan Van Mai, Son Van Ho, Than Thi Nguyen, Lan Thi Thuong Vo

published 07 Jan 2025

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An appropriate DNA input for bisulfite conversion reveals LINE-1 and Alu hypermethylation in tissues and circulating cell-free DNA from cancers

Trang Thi Quynh Tran, Tung The Pham, Than Thi Nguyen, Trang Hien Do, Phuong Thi Thu Luu, Uyen Quynh Nguyen, Linh Dieu Vuong, Quang Ngoc Nguyen, Son Van Ho, Hang Viet Dao, Tong Van Hoang, Lan Thi Thuong Vo

published 30 Dec 2024

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DMRIntTk: Integrating different DMR sets based on density peak clustering

Wenjin Zhang, Wenlong Jie, Wanxin Cui, Guihua Duan, You Zou, Xiaoqing Peng

published 23 Dec 2024

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DFASGCNS: A prognostic model for ovarian cancer prediction based on dual fusion channels and stacked graph convolution

Huiqing Wang, Xiao Han, Shuaijun Niu, Hao Cheng, Jianxue Ren, Yimeng Duan

published 16 Dec 2024

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Impact of combined exercise on blood DNA methylation and physical health in older women with obesity

Atchara Dawangpa, Pitaksin Chitta, Guilherme da Silva Rodrigues, Nutta Iadsee, Natália Y. Noronha, Carla B. Nonino, Carlos R. Bueno Júnior, Chanachai Sae-Lee

published 16 Dec 2024

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Modeling the consequences of age-linked rDNA hypermethylation with dCas9-directed DNA methylation in human cells

Yana Blokhina, Abigail Buchwalter

published 12 Dec 2024

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A novel family of beta mixture models for the differential analysis of DNA methylation data: An application to prostate cancer

Koyel Majumdar, Romina Silva, Antoinette Sabrina Perry, Ronald William Watson, Andrea Rau, Florence Jaffrezic, Thomas Brendan Murphy, Isobel Claire Gormley

published 11 Dec 2024

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Generation of isogenic models of Angelman syndrome and Prader-Willi syndrome in CRISPR/Cas9-engineered human embryonic stem cells

Rachel B. Gilmore, Dea Gorka, Christopher E. Stoddard, Pooja Sonawane, Justin Cotney, Stormy J. Chamberlain

published 01 Nov 2024

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