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DNA modification

Effect of TET inhibitor on bovine parthenogenetic embryo development

Jian Zhang, Sheng Zhang, Yutian Wang, Hui Cheng, Linlin Hao, Yanhui Zhai, Zhiren Zhang, Xinglan An, Xiaoling Ma, Xueming Zhang, Ziyi Li, Bo Tang

published 21 Dec 2017

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Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects

Roy Eldor, Luke Norton, Marcel Fourcaudot, Cynthia Galindo, Ralph A. DeFronzo, Muhammad Abdul-Ghani

published 20 Dec 2017

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High expression of lncRNA PVT1 independently predicts poor overall survival in patients with primary uveal melanoma

Haiming Xu, Jingwen Gong, Hui Liu

published 15 Dec 2017

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Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes

Martha Scott Tomlinson, Paige A. Bommarito, Elizabeth M. Martin, Lisa Smeester, Raina N. Fichorova, Andrew B. Onderdonk, Karl C. K. Kuban, T. Michael O’Shea, Rebecca C. Fry

published 14 Dec 2017

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Attenuated expression of MTR in both prenatally androgenized mice and women with the hyperandrogenic phenotype of PCOS

Lei Lei, Lijun Ding, Jing Su, Mengyuan Liu, Qingqing Shi, Jianjun Zhou, Haixiang Sun, Guijun Yan

published 12 Dec 2017

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Consequences of supplying methyl donors during pregnancy on the methylome of the offspring from lactating and non-lactating dairy cattle

Alex Bach, Anna Aris, Isabel Guasch

published 11 Dec 2017

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Altered intragenic DNA methylation of HOOK2 gene in adipose tissue from individuals with obesity and type 2 diabetes

Sandra Rodríguez-Rodero, Edelmiro Menéndez-Torre, Gustavo Fernández-Bayón, Paula Morales-Sánchez, Lourdes Sanz, Estrella Turienzo, Juan José González, Ceferino Martinez-Faedo, Lorena Suarez-Gutiérrez, Jessica Ares, Lucia Díaz-Naya, Alicia Martin-Nieto, Juan L. Fernández-Morera, Mario F. Fraga, Elías Delgado-Álvarez

published 11 Dec 2017

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DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird

Ricardo De Paoli-Iseppi, Andrea M. Polanowski, Clive McMahon, Bruce E. Deagle, Joanne L. Dickinson, Mark A. Hindell, Simon N. Jarman

published 07 Dec 2017

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Transcription factors, coregulators, and epigenetic marks are linearly correlated and highly redundant

Tobias Ahsendorf, Franz-Josef Müller, Ved Topkar, Jeremy Gunawardena, Roland Eils

published 07 Dec 2017

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Restoration of the prolyl-hydroxylase domain protein-3 oxygen-sensing mechanism is responsible for regulation of HIF2α expression and induction of sensitivity of myeloma cells to hypoxia-mediated apoptosis

Gilberto Gastelum, Aleksandra Poteshkina, Mysore Veena, Edgar Artiga, Geraldine Weckstein, Patrick Frost

published 05 Dec 2017

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Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines

Marek Foksinski, Ewelina Zarakowska, Daniel Gackowski, Magdalena Skonieczna, Karolina Gajda, Dorota Hudy, Anna Szpila, Karol Bialkowski, Marta Starczak, Anna Labejszo, Jaroslaw Czyz, Joanna Rzeszowska-Wolny, Ryszard Olinski

published 30 Nov 2017

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Developmental peculiarities in placentae of ovine uniparental conceptuses

Roberta Arena, Federica Zacchini, Paola Toschi, Luca Palazzese, Marta Czernik, Grażyna Ewa Ptak

published 30 Nov 2017

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Prognostic significance of promoter DNA hypermethylation of the cysteine dioxygenase 1 (CDO1) gene in primary gallbladder cancer and gallbladder disease

Kazuharu Igarashi, Keishi Yamashita, Hiroshi Katoh, Keita Kojima, Yosuke Ooizumi, Nobuyuki Nishizawa, Ryo Nishiyama, Hiroshi Kawamata, Hiroshi Tajima, Takashi Kaizu, Yusuke Kumamoto, Masahiko Watanabe

published 21 Nov 2017

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