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DNA modification

A genome-wide analysis of DNA methylation identifies a novel association signal for Lp(a) concentrations in the LPA promoter

Stefan Coassin, Natascha Hermann-Kleiter, Margot Haun, Simone Wahl, Rory Wilson, Bernhard Paulweber, Sonja Kunze, Thomas Meitinger, Konstantin Strauch, Annette Peters, Melanie Waldenberger, Florian Kronenberg, Claudia Lamina

published 28 Apr 2020

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Associations among smoking, MGMT hypermethylation, TP53-mutations, and relapse in head and neck squamous cell carcinoma

Shinichi Matsuda, Aki Mafune, Nagisa Kohda, Takanori Hama, Mitsuyoshi Urashima

published 23 Apr 2020

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Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer

Ping-Ching Hsu, Susan A. Kadlubar, Eric R. Siegel, Lora J. Rogers, Valentina K. Todorova, L. Joseph Su, Issam Makhoul

published 16 Apr 2020

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DNA methylation biomarkers for nasopharyngeal carcinoma

Baoai Han, Xiuping Yang, Po Zhang, Ya Zhang, Yaqin Tu, Zuhong He, Yongqin Li, Jie Yuan, Yaodong Dong, Davood K. Hosseini, Tao Zhou, Haiying Sun

published 09 Apr 2020

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Interplay between TERT promoter mutations and methylation culminates in chromatin accessibility and TERT expression

Catarina Salgado, Celine Roelse, Rogier Nell, Nelleke Gruis, Remco van Doorn, Pieter van der Velden

published 08 Apr 2020

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Folic acid supplementation alleviates reduced ureteric branching, nephrogenesis, and global DNA methylation induced by maternal nutrient restriction in rat embryonic kidney

Midori Awazu, Mariko Hida

published 06 Apr 2020

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Global expression and CpG methylation analysis of primary endothelial cells before and after TNFa stimulation reveals gene modules enriched in inflammatory and infectious diseases and associated DMRs

Brooke Rhead, Xiaorong Shao, Hong Quach, Poonam Ghai, Lisa F. Barcellos, Anne M. Bowcock

published 31 Mar 2020

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Investigation of the molecular biology underlying the pronounced high gene targeting frequency at the Myh9 gene locus in mouse embryonic stem cells

Lei Tan, Yi Hu, Yalan Li, Lingchen Yang, Xiong Cai, Wei Liu, Jiayi He, Yingxin Wu, Tanbin Liu, Naidong Wang, Yi Yang, Robert S. Adelstein, Aibing Wang

published 30 Mar 2020

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Comparing genome-scale DNA methylation and CNV marks between adult human cultured ITGA6+ testicular cells and seminomas to assess in vitro genomic stability

Robert B. Struijk, Lambert C. J. Dorssers, Peter Henneman, Martin A. Rijlaarsdam, Andrea Venema, Aldo Jongejan, Marcel M. A. M. Mannens, Leendert H. J. Looijenga, Sjoerd Repping, Ans M. M. van Pelt

published 16 Mar 2020

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Evaluation of pre-processing on the meta-analysis of DNA methylation data from the Illumina HumanMethylation450 BeadChip platform

Claudia Sala, Pietro Di Lena, Danielle Fernandes Durso, Andrea Prodi, Gastone Castellani, Christine Nardini

published 10 Mar 2020

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Advanced paternal age directly impacts mouse embryonic placental imprinting

Michelle M. Denomme, Jason C. Parks, Blair R. McCallie, Nathan I. McCubbin, William B. Schoolcraft, Mandy G. Katz-Jaffe

published 06 Mar 2020

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Methylation of SRD5A2 promoter predicts a better outcome for castration-resistant prostate cancer patients undergoing androgen deprivation therapy

Zongwei Wang, Tuo Deng, Xingbo Long, Xueming Lin, Shulin Wu, Hongbo Wang, Rongbin Ge, Zhenwei Zhang, Chin-Lee Wu, Mary-Ellen Taplin, Aria F. Olumi

published 05 Mar 2020

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Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions

Agnieszka Belter, Jakub Barciszewski, Anna-Maria Barciszewska

published 26 Feb 2020

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