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DNA cleavage

Application of a Novel Microtitre Plate-Based Assay for the Discovery of New Inhibitors of DNA Gyrase and DNA Topoisomerase VI

James A. Taylor, Lesley A. Mitchenall, [ ... ], Anthony Maxwell

Gene- and Protein-Delivered Zinc Finger–Staphylococcal Nuclease Hybrid for Inhibition of DNA Replication of Human Papillomavirus

Takashi Mino, Tomoaki Mori, Yasuhiro Aoyama, Takashi Sera

Differential Targeting of Unpaired Bases within Duplex DNA by the Natural Compound Clerocidin: A Valuable Tool to Dissect DNA Secondary Structure

Matteo Nadai, Giorgio Palù, Manlio Palumbo, Sara N. Richter

Atomic Scissors: A New Method of Tracking the 5-Bromo-2′-Deoxyuridine-Labeled DNA In Situ

Anna Ligasová, Dmytro Strunin, [ ... ], Karel Koberna

Highly Mutagenic Exocyclic DNA Adducts Are Substrates for the Human Nucleotide Incision Repair Pathway

Paulina Prorok, Christine Saint-Pierre, [ ... ], Murat Saparbaev

Autophagy and Apoptosis Are Differentially Induced in Neurons and Astrocytes Treated with an In Vitro Mimic of the Ischemic Penumbra

Matthew E. Pamenter, Guy A. Perkins, [ ... ], Gabriel G. Haddad

A Common Origin for the Bacterial Toxin-Antitoxin Systems parD and ccd, Suggested by Analyses of Toxin/Target and Toxin/Antitoxin Interactions

Andrew B. Smith, Juan López-Villarejo, [ ... ], Ramón Díaz-Orejas

The Crucial Role of Divalent Metal Ions in the DNA-Acting Efficacy and Inhibition of the Transcription of Dimeric Chromomycin A3

Chun-Wei Hsu, Show-Mei Chuang, Wen-Ling Wu, Ming-Hon Hou

I-PfoP3I: A Novel Nicking HNH Homing Endonuclease Encoded in the Group I Intron of the DNA Polymerase Gene in Phormidium foveolarum Phage Pf-WMP3

Shuanglei Kong, Xinyao Liu, [ ... ], Chengcai An

Methylation by a Unique α-class N4-Cytosine Methyltransferase Is Required for DNA Transformation of Caldicellulosiruptor bescii DSM6725

Daehwan Chung, Joel Farkas, [ ... ], Janet Westpheling

Cleavage of Phage DNA by the Streptococcus thermophilus CRISPR3-Cas System

Alfonso H. Magadán, Marie-Ève Dupuis, Manuela Villion, Sylvain Moineau

Synthesis and Biological Evaluation of Phenanthrenes as Cytotoxic Agents with Pharmacophore Modeling and ChemGPS-NP Prediction as Topo II Inhibitors

Chia-Lin Lee, Ying-Ting Lin, [ ... ], Yang-Chang Wu

Direct Observation of Strand Passage by DNA-Topoisomerase and Its Limited Processivity

Katsunori Yogo, Taisaku Ogawa, [ ... ], Kazuhiko Kinosita Jr

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