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DNA cleavage

Petri net–based model of the human DNA base excision repair pathway

Marcin Radom, Magdalena A. Machnicka, Joanna Krwawicz, Janusz M. Bujnicki, Piotr Formanowicz

published 13 Sep 2019

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Analyzing dwell times with the Generalized Method of Moments

Sadie Piatt, Allen C. Price

published 08 Jan 2019

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A study on endonuclease BspD6I and its stimulus-responsive switching by modified oligonucleotides

Liudmila A. Abrosimova, Anzhela Yu. Migur, Elena A. Kubareva, Timofei S. Zatsepin, Aleksandra V. Gavshina, Alfiya K. Yunusova, Tatiana A. Perevyazova, Alfred Pingoud, Tatiana S. Oretskaya

published 26 Nov 2018

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Pre-existing technological core and roots for the CRISPR breakthrough

Christopher L. Magee, Patrick W. Kleyn, Brendan M. Monks, Ulrich Betz, Subarna Basnet

published 19 Sep 2018

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Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage

Nachiappan Dhatchana Moorthy, Bose Muthu Ramalingam, Saleem Iqbal, Arasambattu K Mohanakrishnan, Krishnasamy Gunasekaran, Elangovan Vellaichamy

published 06 Sep 2018

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BtsCI and BseGI display sequence preference in the nucleotides flanking the recognition sequence

João Rosa, Esther Fernandez-Gonzalez, Cosimo Ducani, Björn Högberg

published 17 Aug 2018

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Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori

Aigerim Turgimbayeva, Sailau Abeldenov, Dmitry O. Zharkov, Alexander A. Ishchenko, Yerlan Ramankulov, Murat Saparbaev, Bekbolat Khassenov

published 15 Aug 2018

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Unexpected binding behaviors of bacterial Argonautes in human cells cast doubts on their use as targetable gene regulators

Henriette O’Geen, Chonghua Ren, Nicole B. Coggins, Sofie L. Bates, David J. Segal

published 27 Mar 2018

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Parallel mapping with site-directed hydroxyl radicals and micrococcal nuclease reveals structural features of positioned nucleosomes in vivo

Tomohiro Fuse, Koji Katsumata, Koya Morohoshi, Yukio Mukai, Yuichi Ichikawa, Hitoshi Kurumizaka, Akio Yanagida, Takeshi Urano, Hiroaki Kato, Mitsuhiro Shimizu

published 26 Oct 2017

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Thermostable proteins bioprocesses: The activity of restriction endonuclease-methyltransferase from Thermus thermophilus (RM.TthHB27I) cloned in Escherichia coli is critically affected by the codon composition of the synthetic gene

Daria Krefft, Aliaksei Papkov, Agnieszka Zylicz-Stachula, Piotr M. Skowron

published 17 Oct 2017

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Antibacterial small molecules targeting the conserved TOPRIM domain of DNA gyrase

Scott S. Walker, Marc Labroli, Ronald E. Painter, Judyann Wiltsie, Brad Sherborne, Nicholas Murgolo, Xinwei Sher, Paul Mann, Paul Zuck, Charles G. Garlisi, Jing Su, Stacia Kargman, Li Xiao, Giovanna Scapin, Scott Salowe, Kristine Devito, Payal Sheth, Nichole Buist, Christopher M. Tan, Todd A. Black, Terry Roemer

published 10 Jul 2017

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DNA recognition by an RNA-guided bacterial Argonaute

Kevin W. Doxzen, Jennifer A. Doudna

published 17 May 2017

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RNA and DNA Targeting by a Reconstituted Thermus thermophilus Type III-A CRISPR-Cas System

Tina Y. Liu, Anthony T. Iavarone, Jennifer A. Doudna

published 23 Jan 2017

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